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HER2-driven breast cancer suppression by the JNK signaling pathway.
Itah Z, Chaudhry S, Raju Ponny S, Aydemir O, Lee A, Cavanagh-Kyros J, Tournier C, Muller WJ, Davis RJ. Itah Z, et al. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2218373120. doi: 10.1073/pnas.2218373120. Epub 2023 Jan 19. Proc Natl Acad Sci U S A. 2023. PMID: 36656864 Free PMC article.
HER2Δ16 Engages ENPP1 to Promote an Immune-Cold Microenvironment in Breast Cancer.
Attalla SS, Boucher J, Proud H, Taifour T, Zuo D, Sanguin-Gendreau V, Ling C, Johnson G, Li V, Luo RB, Kuasne H, Papavasiliou V, Walsh LA, Barok M, Joensuu H, Park M, Roux PP, Muller WJ. Attalla SS, et al. Cancer Immunol Res. 2023 Sep 1;11(9):1184-1202. doi: 10.1158/2326-6066.CIR-22-0140. Cancer Immunol Res. 2023. PMID: 37311021
Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides.
Hulea L, Gravel SP, Morita M, Cargnello M, Uchenunu O, Im YK, Lehuédé C, Ma EH, Leibovitch M, McLaughlan S, Blouin MJ, Parisotto M, Papavasiliou V, Lavoie C, Larsson O, Ohh M, Ferreira T, Greenwood C, Bridon G, Avizonis D, Ferbeyre G, Siegel P, Jones RG, Muller W, Ursini-Siegel J, St-Pierre J, Pollak M, Topisirovic I. Hulea L, et al. Cell Metab. 2018 Dec 4;28(6):817-832.e8. doi: 10.1016/j.cmet.2018.09.001. Epub 2018 Sep 20. Cell Metab. 2018. PMID: 30244971 Free PMC article.
An ErbB2 splice variant lacking exon 16 drives lung carcinoma.
Smith HW, Yang L, Ling C, Walsh A, Martinez VD, Boucher J, Zuo D, Sokol ES, Pavlick DC, Frampton GM, Chmielecki J, Jones LM, Roux PP, Lockwood WW, Muller WJ. Smith HW, et al. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20139-20148. doi: 10.1073/pnas.2007474117. Epub 2020 Jul 29. Proc Natl Acad Sci U S A. 2020. PMID: 32727899 Free PMC article.