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Severe infections emerge from commensal bacteria by adaptive evolution.
Young BC, Wu CH, Gordon NC, Cole K, Price JR, Liu E, Sheppard AE, Perera S, Charlesworth J, Golubchik T, Iqbal Z, Bowden R, Massey RC, Paul J, Crook DW, Peto TE, Walker AS, Llewelyn MJ, Wyllie DH, Wilson DJ. Young BC, et al. Elife. 2017 Dec 19;6:e30637. doi: 10.7554/eLife.30637. Elife. 2017. PMID: 29256859 Free PMC article.
Same-Day Diagnostic and Surveillance Data for Tuberculosis via Whole-Genome Sequencing of Direct Respiratory Samples.
Votintseva AA, Bradley P, Pankhurst L, Del Ojo Elias C, Loose M, Nilgiriwala K, Chatterjee A, Smith EG, Sanderson N, Walker TM, Morgan MR, Wyllie DH, Walker AS, Peto TEA, Crook DW, Iqbal Z. Votintseva AA, et al. J Clin Microbiol. 2017 May;55(5):1285-1298. doi: 10.1128/JCM.02483-16. Epub 2017 Mar 8. J Clin Microbiol. 2017. PMID: 28275074 Free PMC article.
Rapid antibiotic-resistance predictions from genome sequence data for Staphylococcus aureus and Mycobacterium tuberculosis.
Bradley P, Gordon NC, Walker TM, Dunn L, Heys S, Huang B, Earle S, Pankhurst LJ, Anson L, de Cesare M, Piazza P, Votintseva AA, Golubchik T, Wilson DJ, Wyllie DH, Diel R, Niemann S, Feuerriegel S, Kohl TA, Ismail N, Omar SV, Smith EG, Buck D, McVean G, Walker AS, Peto TE, Crook DW, Iqbal Z. Bradley P, et al. Nat Commun. 2015 Dec 21;6:10063. doi: 10.1038/ncomms10063. Nat Commun. 2015. PMID: 26686880 Free PMC article.
Evaluation of Whole-Genome Sequencing for Mycobacterial Species Identification and Drug Susceptibility Testing in a Clinical Setting: a Large-Scale Prospective Assessment of Performance against Line Probe Assays and Phenotyping.
Quan TP, Bawa Z, Foster D, Walker T, Del Ojo Elias C, Rathod P; MMM Informatics Group; Iqbal Z, Bradley P, Mowbray J, Walker AS, Crook DW, Wyllie DH, Peto TEA, Smith EG. Quan TP, et al. J Clin Microbiol. 2018 Jan 24;56(2):e01480-17. doi: 10.1128/JCM.01480-17. Print 2018 Feb. J Clin Microbiol. 2018. PMID: 29167290 Free PMC article.