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SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation.
Nat Metab. 2021 Sep;3(9):1150-1162. doi: 10.1038/s42255-021-00440-5. Epub 2021 Sep 16.
Nat Metab. 2021.
PMID: 34531575
Free PMC article.
C13orf31 (FAMIN) is a central regulator of immunometabolic function.
Cader MZ, Boroviak K, Zhang Q, Assadi G, Kempster SL, Sewell GW, Saveljeva S, Ashcroft JW, Clare S, Mukhopadhyay S, Brown KP, Tschurtschenthaler M, Raine T, Doe B, Chilvers ER, Griffin JL, Kaneider NC, Floto RA, D'Amato M, Bradley A, Wakelam MJ, Dougan G, Kaser A.
Cader MZ, et al.
Nat Immunol. 2016 Sep;17(9):1046-56. doi: 10.1038/ni.3532. Epub 2016 Aug 1.
Nat Immunol. 2016.
PMID: 27478939
Free PMC article.
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