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Year Number of Results
2014 6
2015 11
2016 4
2018 3
2019 7
2020 12
2021 5
2022 5
2023 1
2024 1

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48 results

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Page 1
The guidance receptor plexin D1 is a mechanosensor in endothelial cells.
Mehta V, Pang KL, Rozbesky D, Nather K, Keen A, Lachowski D, Kong Y, Karia D, Ameismeier M, Huang J, Fang Y, Del Rio Hernandez A, Reader JS, Jones EY, Tzima E. Mehta V, et al. Nature. 2020 Feb;578(7794):290-295. doi: 10.1038/s41586-020-1979-4. Epub 2020 Feb 5. Nature. 2020. PMID: 32025034 Free PMC article.
NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.
Flanagan DJ, Pentinmikko N, Luopajärvi K, Willis NJ, Gilroy K, Raven AP, Mcgarry L, Englund JI, Webb AT, Scharaw S, Nasreddin N, Hodder MC, Ridgway RA, Minnee E, Sphyris N, Gilchrist E, Najumudeen AK, Romagnolo B, Perret C, Williams AC, Clevers H, Nummela P, Lähde M, Alitalo K, Hietakangas V, Hedley A, Clark W, Nixon C, Kirschner K, Jones EY, Ristimäki A, Leedham SJ, Fish PV, Vincent JP, Katajisto P, Sansom OJ. Flanagan DJ, et al. Nature. 2021 Jun;594(7863):430-435. doi: 10.1038/s41586-021-03525-z. Epub 2021 Jun 2. Nature. 2021. PMID: 34079124 Free PMC article.
Small-molecule inhibitors of carboxylesterase Notum.
Zhao Y, Jolly S, Benvegnu S, Jones EY, Fish PV. Zhao Y, et al. Future Med Chem. 2021 Jun;13(11):1001-1015. doi: 10.4155/fmc-2021-0036. Epub 2021 Apr 22. Future Med Chem. 2021. PMID: 33882714 Free PMC article. Review.
Structural Perspectives on Axon Guidance.
Seiradake E, Jones EY, Klein R. Seiradake E, et al. Annu Rev Cell Dev Biol. 2016 Oct 6;32:577-608. doi: 10.1146/annurev-cellbio-111315-125008. Epub 2016 Aug 24. Annu Rev Cell Dev Biol. 2016. PMID: 27576119 Review.
Extracellular modulators of Wnt signalling.
Malinauskas T, Jones EY. Malinauskas T, et al. Curr Opin Struct Biol. 2014 Dec;29:77-84. doi: 10.1016/j.sbi.2014.10.003. Epub 2014 Oct 20. Curr Opin Struct Biol. 2014. PMID: 25460271 Free article. Review.
Notum deacylates octanoylated ghrelin.
Zhao Y, Schuhmacher LN, Roberts M, Kakugawa S, Bineva-Todd G, Howell S, O'Reilly N, Perret C, Snijders AP, Vincent JP, Jones EY. Zhao Y, et al. Mol Metab. 2021 Jul;49:101201. doi: 10.1016/j.molmet.2021.101201. Epub 2021 Feb 27. Mol Metab. 2021. PMID: 33647468 Free PMC article.
Structural Insights into Notum Covalent Inhibition.
Zhao Y, Svensson F, Steadman D, Frew S, Monaghan A, Bictash M, Moreira T, Chalk R, Lu W, Fish PV, Jones EY. Zhao Y, et al. J Med Chem. 2021 Aug 12;64(15):11354-11363. doi: 10.1021/acs.jmedchem.1c00701. Epub 2021 Jul 22. J Med Chem. 2021. PMID: 34292747 Free PMC article.
Structural Analysis and Development of Notum Fragment Screening Hits.
Zhao Y, Mahy W, Willis NJ, Woodward HL, Steadman D, Bayle ED, Atkinson BN, Sipthorp J, Vecchia L, Ruza RR, Harlos K, Jeganathan F, Constantinou S, Costa A, Kjær S, Bictash M, Salinas PC, Whiting P, Vincent JP, Fish PV, Jones EY. Zhao Y, et al. ACS Chem Neurosci. 2022 Jul 6;13(13):2060-2077. doi: 10.1021/acschemneuro.2c00325. Epub 2022 Jun 22. ACS Chem Neurosci. 2022. PMID: 35731924 Free PMC article.
Structural basis of semaphorin-plexin cis interaction.
Rozbesky D, Verhagen MG, Karia D, Nagy GN, Alvarez L, Robinson RA, Harlos K, Padilla-Parra S, Pasterkamp RJ, Jones EY. Rozbesky D, et al. EMBO J. 2020 Jul 1;39(13):e102926. doi: 10.15252/embj.2019102926. Epub 2020 Jun 5. EMBO J. 2020. PMID: 32500924 Free PMC article.
48 results