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The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response.
Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, Zacchigna S, Mukherjee S, Chen DJ, Mahmoud AI, Giacca M, Rabinovitch PS, Aroumougame A, Shah AM, Szweda LI, Sadek HA. Puente BN, et al. Cell. 2014 Apr 24;157(3):565-79. doi: 10.1016/j.cell.2014.03.032. Cell. 2014. PMID: 24766806 Free PMC article.
Meis1 regulates postnatal cardiomyocyte cell cycle arrest.
Mahmoud AI, Kocabas F, Muralidhar SA, Kimura W, Koura AS, Thet S, Porrello ER, Sadek HA. Mahmoud AI, et al. Nature. 2013 May 9;497(7448):249-253. doi: 10.1038/nature12054. Epub 2013 Apr 17. Nature. 2013. PMID: 23594737 Free PMC article.
Surgical models for cardiac regeneration in neonatal mice.
Mahmoud AI, Porrello ER, Kimura W, Olson EN, Sadek HA. Mahmoud AI, et al. Nat Protoc. 2014 Feb;9(2):305-11. doi: 10.1038/nprot.2014.021. Epub 2014 Jan 16. Nat Protoc. 2014. PMID: 24434799 Free PMC article.
Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family.
Porrello ER, Mahmoud AI, Simpson E, Johnson BA, Grinsfelder D, Canseco D, Mammen PP, Rothermel BA, Olson EN, Sadek HA. Porrello ER, et al. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):187-92. doi: 10.1073/pnas.1208863110. Epub 2012 Dec 17. Proc Natl Acad Sci U S A. 2013. PMID: 23248315 Free PMC article.