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Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy.
Oncotarget. 2014 Mar 30;5(6):1646-56. doi: 10.18632/oncotarget.1802.
Oncotarget. 2014.
PMID: 24722067
Free PMC article.
Androgen receptor splice variants determine taxane sensitivity in prostate cancer.
Thadani-Mulero M, Portella L, Sun S, Sung M, Matov A, Vessella RL, Corey E, Nanus DM, Plymate SR, Giannakakou P.
Thadani-Mulero M, et al.
Cancer Res. 2014 Apr 15;74(8):2270-2282. doi: 10.1158/0008-5472.CAN-13-2876. Epub 2014 Feb 20.
Cancer Res. 2014.
PMID: 24556717
Free PMC article.
In contrast, the microtubule-interacting splice variant ARv567 was sensitive to taxane-induced microtubule stabilization. In ARv567-expressing LuCap86.2 tumor xenografts, docetaxel treatment was highly efficacious, whereas ARv7-expressing LuCap23.1 tumor xenografts display …
In contrast, the microtubule-interacting splice variant ARv567 was sensitive to taxane-induced microtubule stabilization. In ARv567-expressi …
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