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Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice.
Lewis JE, Woodward OR, Nuzzaci D, Smith CA, Adriaenssens AE, Billing L, Brighton C, Phillips BU, Tadross JA, Kinston SJ, Ciabatti E, Göttgens B, Tripodi M, Hornigold D, Baker D, Gribble FM, Reimann F. Lewis JE, et al. Mol Metab. 2022 Dec;66:101604. doi: 10.1016/j.molmet.2022.101604. Epub 2022 Sep 30. Mol Metab. 2022. PMID: 36184065 Free PMC article.
Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding.
Adriaenssens A, Broichhagen J, de Bray A, Ast J, Hasib A, Jones B, Tomas A, Burgos NF, Woodward O, Lewis J, O'Flaherty E, El K, Cui C, Harada N, Inagaki N, Campbell J, Brierley D, Hodson DJ, Samms R, Gribble F, Reimann F. Adriaenssens A, et al. JCI Insight. 2023 May 22;8(10):e164921. doi: 10.1172/jci.insight.164921. JCI Insight. 2023. PMID: 37212283 Free PMC article.