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Origins of the cytolytic synapse.
de la Roche M, Asano Y, Griffiths GM. de la Roche M, et al. Nat Rev Immunol. 2016 Jul;16(7):421-32. doi: 10.1038/nri.2016.54. Epub 2016 Jun 6. Nat Rev Immunol. 2016. PMID: 27265595 Review.
Primary Cilia Mediate Diverse Kinase Inhibitor Resistance Mechanisms in Cancer.
Jenks AD, Vyse S, Wong JP, Kostaras E, Keller D, Burgoyne T, Shoemark A, Tsalikis A, de la Roche M, Michaelis M, Cinatl J Jr, Huang PH, Tanos BE. Jenks AD, et al. Cell Rep. 2018 Jun 5;23(10):3042-3055. doi: 10.1016/j.celrep.2018.05.016. Cell Rep. 2018. PMID: 29874589 Free PMC article.
Aging increases cell-to-cell transcriptional variability upon immune stimulation.
Martinez-Jimenez CP, Eling N, Chen HC, Vallejos CA, Kolodziejczyk AA, Connor F, Stojic L, Rayner TF, Stubbington MJT, Teichmann SA, de la Roche M, Marioni JC, Odom DT. Martinez-Jimenez CP, et al. Science. 2017 Mar 31;355(6332):1433-1436. doi: 10.1126/science.aah4115. Science. 2017. PMID: 28360329 Free PMC article.
A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo.
Cassidy LD, Young AR, Pérez-Mancera PA, Nimmervoll B, Jaulim A, Chen HC, McIntyre DJO, Brais R, Ricketts T, Pacey S, De La Roche M, Gilbertson RJ, Rubinsztein DC, Narita M. Cassidy LD, et al. Autophagy. 2018;14(7):1256-1266. doi: 10.1080/15548627.2018.1458172. Epub 2018 Jul 12. Autophagy. 2018. PMID: 29999454 Free PMC article.