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Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340.
Sci Immunol. 2021.
PMID: 34413139
Free PMC article.
High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape.
Schmidt F, Weisblum Y, Rutkowska M, Poston D, DaSilva J, Zhang F, Bednarski E, Cho A, Schaefer-Babajew DJ, Gaebler C, Caskey M, Nussenzweig MC, Hatziioannou T, Bieniasz PD.
Schmidt F, et al.
Nature. 2021 Dec;600(7889):512-516. doi: 10.1038/s41586-021-04005-0. Epub 2021 Sep 20.
Nature. 2021.
PMID: 34544114
Free PMC article.
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Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection.
Wang Z, Muecksch F, Schaefer-Babajew D, Finkin S, Viant C, Gaebler C, Hoffmann HH, Barnes CO, Cipolla M, Ramos V, Oliveira TY, Cho A, Schmidt F, Da Silva J, Bednarski E, Aguado L, Yee J, Daga M, Turroja M, Millard KG, Jankovic M, Gazumyan A, Zhao Z, Rice CM, Bieniasz PD, Caskey M, Hatziioannou T, Nussenzweig MC.
Wang Z, et al.
Nature. 2021 Jul;595(7867):426-431. doi: 10.1038/s41586-021-03696-9. Epub 2021 Jun 14.
Nature. 2021.
PMID: 34126625
Free PMC article.
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Anti-SARS-CoV-2 receptor-binding domain antibody evolution after mRNA vaccination.
Cho A, Muecksch F, Schaefer-Babajew D, Wang Z, Finkin S, Gaebler C, Ramos V, Cipolla M, Mendoza P, Agudelo M, Bednarski E, DaSilva J, Shimeliovich I, Dizon J, Daga M, Millard KG, Turroja M, Schmidt F, Zhang F, Tanfous TB, Jankovic M, Oliveria TY, Gazumyan A, Caskey M, Bieniasz PD, Hatziioannou T, Nussenzweig MC.
Cho A, et al.
Nature. 2021 Dec;600(7889):517-522. doi: 10.1038/s41586-021-04060-7. Epub 2021 Oct 7.
Nature. 2021.
PMID: 34619745
Free PMC article.
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