323040/ERC_/European Research Council/International[Grants and Funding] - Search Results

Year	Number of Results
2015	1
2016	3
2017	2
2019	1
2020	1
2021	1
2024	0

1

RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation.

Lin J, Kumari S, Kim C, Van TM, Wachsmuth L, Polykratis A, Pasparakis M. Lin J, et al. Nature. 2016 Dec 1;540(7631):124-128. doi: 10.1038/nature20558. Epub 2016 Nov 7. Nature. 2016. PMID: 27819681 Free PMC article.

2

FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells.

Schwarzer R, Jiao H, Wachsmuth L, Tresch A, Pasparakis M. Schwarzer R, et al. Immunity. 2020 Jun 16;52(6):978-993.e6. doi: 10.1016/j.immuni.2020.04.002. Epub 2020 May 1. Immunity. 2020. PMID: 32362323 Free article.

3

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.

Ito Y, Ofengeim D, Najafov A, Das S, Saberi S, Li Y, Hitomi J, Zhu H, Chen H, Mayo L, Geng J, Amin P, DeWitt JP, Mookhtiar AK, Florez M, Ouchida AT, Fan JB, Pasparakis M, Kelliher MA, Ravits J, Yuan J. Ito Y, et al. Science. 2016 Aug 5;353(6299):603-8. doi: 10.1126/science.aaf6803. Science. 2016. PMID: 27493188 Free PMC article.

4

The interplay of IKK, NF-κB and RIPK1 signaling in the regulation of cell death, tissue homeostasis and inflammation.

Kondylis V, Kumari S, Vlantis K, Pasparakis M. Kondylis V, et al. Immunol Rev. 2017 May;277(1):113-127. doi: 10.1111/imr.12550. Immunol Rev. 2017. PMID: 28462531 Review.

5

Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis.

Van TM, Polykratis A, Straub BK, Kondylis V, Papadopoulou N, Pasparakis M. Van TM, et al. J Clin Invest. 2017 Jun 30;127(7):2662-2677. doi: 10.1172/JCI92508. Epub 2017 Jun 19. J Clin Invest. 2017. PMID: 28628031 Free PMC article.

6

Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF.

Hausmann A, Felmy B, Kunz L, Kroon S, Berthold DL, Ganz G, Sandu I, Nakamura T, Zangger NS, Zhang Y, Dolowschiak T, Fattinger SA, Furter M, Müller-Hauser AA, Barthel M, Vlantis K, Wachsmuth L, Kisielow J, Tortola L, Heide D, Heikenwälder M, Oxenius A, Kopf M, Schroeder T, Pasparakis M, Sellin ME, Hardt WD. Hausmann A, et al. J Exp Med. 2021 Nov 1;218(11):e20210862. doi: 10.1084/jem.20210862. Epub 2021 Sep 16. J Exp Med. 2021. PMID: 34529751 Free PMC article.

7

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis.

Kondylis V, Polykratis A, Ehlken H, Ochoa-Callejero L, Straub BK, Krishna-Subramanian S, Van TM, Curth HM, Heise N, Weih F, Klein U, Schirmacher P, Kelliher M, Pasparakis M. Kondylis V, et al. Cancer Cell. 2015 Nov 9;28(5):582-598. doi: 10.1016/j.ccell.2015.10.001. Cancer Cell. 2015. PMID: 26555174 Free PMC article.

8

RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury.

Krishna-Subramanian S, Singer S, Armaka M, Banales JM, Holzer K, Schirmacher P, Walczak H, Kollias G, Pasparakis M, Kondylis V. Krishna-Subramanian S, et al. Cell Death Differ. 2019 Dec;26(12):2710-2726. doi: 10.1038/s41418-019-0330-9. Epub 2019 Apr 15. Cell Death Differ. 2019. PMID: 30988397 Free PMC article.

9

Transplantation from a symptomatic carrier sister restores host defenses but does not prevent colitis in NEMO deficiency.

Klemann C, Pannicke U, Morris-Rosendahl DJ, Vlantis K, Rizzi M, Uhlig H, Vraetz T, Speckmann C, Strahm B, Pasparakis M, Schwarz K, Ehl S, Rohr JC. Klemann C, et al. Clin Immunol. 2016 Mar;164:52-6. doi: 10.1016/j.clim.2016.01.010. Epub 2016 Jan 23. Clin Immunol. 2016. PMID: 26812624 Free PMC article.

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