A17257/CRUK_/Cancer Research UK/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2015	5
2016	2
2018	1
2019	2
2020	3
2021	2
2023	2
2024	0

1

Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin.

Martincorena I, Roshan A, Gerstung M, Ellis P, Van Loo P, McLaren S, Wedge DC, Fullam A, Alexandrov LB, Tubio JM, Stebbings L, Menzies A, Widaa S, Stratton MR, Jones PH, Campbell PJ. Martincorena I, et al. Science. 2015 May 22;348(6237):880-6. doi: 10.1126/science.aaa6806. Science. 2015. PMID: 25999502 Free PMC article.

2

Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium.

Colom B, Alcolea MP, Piedrafita G, Hall MWJ, Wabik A, Dentro SC, Fowler JC, Herms A, King C, Ong SH, Sood RK, Gerstung M, Martincorena I, Hall BA, Jones PH. Colom B, et al. Nat Genet. 2020 Jun;52(6):604-614. doi: 10.1038/s41588-020-0624-3. Epub 2020 May 18. Nat Genet. 2020. PMID: 32424351 Free PMC article.

3

Switching roles: the functional plasticity of adult tissue stem cells.

Wabik A, Jones PH. Wabik A, et al. EMBO J. 2015 May 5;34(9):1164-79. doi: 10.15252/embj.201490386. Epub 2015 Mar 26. EMBO J. 2015. PMID: 25812989 Free PMC article. Review.

4

Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.

Abby E, Dentro SC, Hall MWJ, Fowler JC, Ong SH, Sood R, Herms A, Piedrafita G, Abnizova I, Siebel CW, Gerstung M, Hall BA, Jones PH. Abby E, et al. Nat Genet. 2023 Feb;55(2):232-245. doi: 10.1038/s41588-022-01280-z. Epub 2023 Jan 19. Nat Genet. 2023. PMID: 36658434 Free PMC article.

5

Cell competition: winning out by losing notch.

Alcolea MP, Jones PH. Alcolea MP, et al. Cell Cycle. 2015;14(1):9-17. doi: 10.4161/15384101.2014.988027. Cell Cycle. 2015. PMID: 25551772 Free PMC article.

6

Relating evolutionary selection and mutant clonal dynamics in normal epithelia.

Hall MWJ, Jones PH, Hall BA. Hall MWJ, et al. J R Soc Interface. 2019 Jul 26;16(156):20190230. doi: 10.1098/rsif.2019.0230. Epub 2019 Jul 31. J R Soc Interface. 2019. PMID: 31362624 Free PMC article.

7

Selection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site.

Fowler JC, King C, Bryant C, Hall MWJ, Sood R, Ong SH, Earp E, Fernandez-Antoran D, Koeppel J, Dentro SC, Shorthouse D, Durrani A, Fife K, Rytina E, Milne D, Roshan A, Mahububani K, Saeb-Parsy K, Hall BA, Gerstung M, Jones PH. Fowler JC, et al. Cancer Discov. 2021 Feb;11(2):340-361. doi: 10.1158/2159-8290.CD-20-1092. Epub 2020 Oct 21. Cancer Discov. 2021. PMID: 33087317 Free PMC article.

8

Mutations observed in somatic evolution reveal underlying gene mechanisms.

Hall MWJ, Shorthouse D, Alcraft R, Jones PH, Hall BA. Hall MWJ, et al. Commun Biol. 2023 Jul 19;6(1):753. doi: 10.1038/s42003-023-05136-y. Commun Biol. 2023. PMID: 37468606 Free PMC article.

9

Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation.

Fernandez-Antoran D, Piedrafita G, Murai K, Ong SH, Herms A, Frezza C, Jones PH. Fernandez-Antoran D, et al. Cell Stem Cell. 2019 Sep 5;25(3):329-341.e6. doi: 10.1016/j.stem.2019.06.011. Epub 2019 Jul 18. Cell Stem Cell. 2019. PMID: 31327664 Free PMC article.

10

Clock-like mutational processes in human somatic cells.

Alexandrov LB, Jones PH, Wedge DC, Sale JE, Campbell PJ, Nik-Zainal S, Stratton MR. Alexandrov LB, et al. Nat Genet. 2015 Dec;47(12):1402-7. doi: 10.1038/ng.3441. Epub 2015 Nov 9. Nat Genet. 2015. PMID: 26551669 Free PMC article.

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