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Year | Number of Results |
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2018 | 1 |
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The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis.
Mol Neurobiol. 2023 Sep;60(9):5034-5054. doi: 10.1007/s12035-023-03355-2. Epub 2023 May 27.
Mol Neurobiol. 2023.
PMID: 37243816
Free PMC article.
Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy.
Lee A, Rayner SL, Gwee SSL, De Luca A, Shahheydari H, Sundaramoorthy V, Ragagnin A, Morsch M, Radford R, Galper J, Freckleton S, Shi B, Walker AK, Don EK, Cole NJ, Yang S, Williams KL, Yerbury JJ, Blair IP, Atkin JD, Molloy MP, Chung RS.
Lee A, et al.
Cell Mol Life Sci. 2018 Jan;75(2):335-354. doi: 10.1007/s00018-017-2632-8. Epub 2017 Aug 29.
Cell Mol Life Sci. 2018.
PMID: 28852778
Free PMC article.
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Using proteomics to identify ubiquitin ligase-substrate pairs: how novel methods may unveil therapeutic targets for neurodegenerative diseases.
Rayner SL, Morsch M, Molloy MP, Shi B, Chung R, Lee A.
Rayner SL, et al.
Cell Mol Life Sci. 2019 Jul;76(13):2499-2510. doi: 10.1007/s00018-019-03082-9. Epub 2019 Mar 27.
Cell Mol Life Sci. 2019.
PMID: 30919022
Free PMC article.
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