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IGM is required for efficient complement mediated phagocytosis of apoptotic cells in vivo.
Autoimmunity. 2005 Jun;38(4):259-64. doi: 10.1080/08916930500124452.
Autoimmunity. 2005.
PMID: 16206508
I-PLA(2) activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation.
Kim SJ, Gershov D, Ma X, Brot N, Elkon KB.
Kim SJ, et al.
J Exp Med. 2002 Sep 2;196(5):655-65. doi: 10.1084/jem.20020542.
J Exp Med. 2002.
PMID: 12208880
Free PMC article.
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