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Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP.
Br J Haematol. 2009 Jan;144(2):245-50. doi: 10.1111/j.1365-2141.2008.07435.x. Epub 2008 Nov 7.
Br J Haematol. 2009.
PMID: 19016713
Free PMC article.
The bisphosphonate zoledronic acid has antimyeloma activity in vivo by inhibition of protein prenylation.
Guenther A, Gordon S, Tiemann M, Burger R, Bakker F, Green JR, Baum W, Roelofs AJ, Rogers MJ, Gramatzki M.
Guenther A, et al.
Int J Cancer. 2010 Jan 1;126(1):239-46. doi: 10.1002/ijc.24758.
Int J Cancer. 2010.
PMID: 19621390
Free article.
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