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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2010 | 4 |
2011 | 2 |
2018 | 1 |
2024 | 0 |
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6 results
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Page 1
Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents.
Drug Metab Rev. 2011 May;43(2):92-137. doi: 10.3109/03602532.2011.567391.
Drug Metab Rev. 2011.
PMID: 21495793
Review.
Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway.
Hayes JD, McMahon M, Chowdhry S, Dinkova-Kostova AT.
Hayes JD, et al.
Antioxid Redox Signal. 2010 Dec 1;13(11):1713-48. doi: 10.1089/ars.2010.3221. Epub 2010 Aug 14.
Antioxid Redox Signal. 2010.
PMID: 20446772
Review.
Item in Clipboard
The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics.
Higgins LG, Hayes JD.
Higgins LG, et al.
Chem Biol Interact. 2011 Jun 30;192(1-2):37-45. doi: 10.1016/j.cbi.2010.09.025. Epub 2010 Oct 23.
Chem Biol Interact. 2011.
PMID: 20932822
Item in Clipboard
Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals.
McMahon M, Lamont DJ, Beattie KA, Hayes JD.
McMahon M, et al.
Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18838-43. doi: 10.1073/pnas.1007387107. Epub 2010 Oct 18.
Proc Natl Acad Sci U S A. 2010.
PMID: 20956331
Free PMC article.
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Zinc-binding triggers a conformational-switch in the cullin-3 substrate adaptor protein KEAP1 that controls transcription factor NRF2.
McMahon M, Swift SR, Hayes JD.
McMahon M, et al.
Toxicol Appl Pharmacol. 2018 Dec 1;360:45-57. doi: 10.1016/j.taap.2018.09.033. Epub 2018 Sep 24.
Toxicol Appl Pharmacol. 2018.
PMID: 30261176
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p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.
Jain A, Lamark T, Sjøttem E, Larsen KB, Awuh JA, Øvervatn A, McMahon M, Hayes JD, Johansen T.
Jain A, et al.
J Biol Chem. 2010 Jul 16;285(29):22576-91. doi: 10.1074/jbc.M110.118976. Epub 2010 May 7.
J Biol Chem. 2010.
PMID: 20452972
Free PMC article.
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