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Increased body mass index is linked to systemic inflammation through altered chromatin co-accessibility in human preadipocytes.
Nat Commun. 2023 Jul 14;14(1):4214. doi: 10.1038/s41467-023-39919-y.
Nat Commun. 2023.
PMID: 37452040
Free PMC article.
Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes.
Pan DZ, Miao Z, Comenho C, Rajkumar S, Koka A, Lee SHT, Alvarez M, Kaminska D, Ko A, Sinsheimer JS, Mohlke KL, Mancuso N, Muñoz-Hernandez LL, Herrera-Hernandez M, Tusié-Luna MT, Aguilar-Salinas C, Pietiläinen KH, Pihlajamäki J, Laakso M, Garske KM, Pajukanta P.
Pan DZ, et al.
Genome Med. 2021 Aug 2;13(1):123. doi: 10.1186/s13073-021-00939-2.
Genome Med. 2021.
PMID: 34340684
Free PMC article.
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Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans.
Garske KM, Pan DZ, Miao Z, Bhagat YV, Comenho C, Robles CR, Benhammou JN, Alvarez M, Ko A, Ye CJ, Pisegna JR, Mohlke KL, Sinsheimer JS, Laakso M, Pajukanta P.
Garske KM, et al.
Nat Metab. 2019 Jun;1(6):630-642. doi: 10.1038/s42255-019-0071-6. Epub 2019 Jun 14.
Nat Metab. 2019.
PMID: 31538139
Free PMC article.
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Phenotype-Specific Enrichment of Mendelian Disorder Genes near GWAS Regions across 62 Complex Traits.
Freund MK, Burch KS, Shi H, Mancuso N, Kichaev G, Garske KM, Pan DZ, Miao Z, Mohlke KL, Laakso M, Pajukanta P, Pasaniuc B, Arboleda VA.
Freund MK, et al.
Am J Hum Genet. 2018 Oct 4;103(4):535-552. doi: 10.1016/j.ajhg.2018.08.017.
Am J Hum Genet. 2018.
PMID: 30290150
Free PMC article.
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