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BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.
Science. 2011 Oct 28;334(6055):525-8. doi: 10.1126/science.1209909.
Science. 2011.
PMID: 22034435
Free PMC article.
E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks.
Reid LJ, Shakya R, Modi AP, Lokshin M, Cheng JT, Jasin M, Baer R, Ludwig T.
Reid LJ, et al.
Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20876-81. doi: 10.1073/pnas.0811203106. Epub 2008 Dec 16.
Proc Natl Acad Sci U S A. 2008.
PMID: 19088202
Free PMC article.
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