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Table representation of search results timeline featuring number of search results per year.
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Page 1
Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer.
Nat Cancer. 2022 Jun;3(6):681-695. doi: 10.1038/s43018-022-00360-7. Epub 2022 Apr 18.
Nat Cancer. 2022.
PMID: 35437317
Free PMC article.
Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-Mediated Targeted Protein Degradation.
Burslem GM, Schultz AR, Bondeson DP, Eide CA, Savage Stevens SL, Druker BJ, Crews CM.
Burslem GM, et al.
Cancer Res. 2019 Sep 15;79(18):4744-4753. doi: 10.1158/0008-5472.CAN-19-1236. Epub 2019 Jul 16.
Cancer Res. 2019.
PMID: 31311809
Free PMC article.
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The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study.
Burslem GM, Smith BE, Lai AC, Jaime-Figueroa S, McQuaid DC, Bondeson DP, Toure M, Dong H, Qian Y, Wang J, Crew AP, Hines J, Crews CM.
Burslem GM, et al.
Cell Chem Biol. 2018 Jan 18;25(1):67-77.e3. doi: 10.1016/j.chembiol.2017.09.009. Epub 2017 Nov 9.
Cell Chem Biol. 2018.
PMID: 29129716
Free PMC article.
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Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead.
Bondeson DP, Smith BE, Burslem GM, Buhimschi AD, Hines J, Jaime-Figueroa S, Wang J, Hamman BD, Ishchenko A, Crews CM.
Bondeson DP, et al.
Cell Chem Biol. 2018 Jan 18;25(1):78-87.e5. doi: 10.1016/j.chembiol.2017.09.010. Epub 2017 Nov 9.
Cell Chem Biol. 2018.
PMID: 29129718
Free PMC article.
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Targeted Protein Degradation by Small Molecules.
Bondeson DP, Crews CM.
Bondeson DP, et al.
Annu Rev Pharmacol Toxicol. 2017 Jan 6;57:107-123. doi: 10.1146/annurev-pharmtox-010715-103507. Epub 2016 Oct 12.
Annu Rev Pharmacol Toxicol. 2017.
PMID: 27732798
Free PMC article.
Review.
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An In Vitro Pull-down Assay of the E3 Ligase:PROTAC:Substrate Ternary Complex to Identify Effective PROTACs.
Bondeson DP, Smith BE, Buhimschi AD.
Bondeson DP, et al.
Methods Mol Biol. 2021;2365:135-150. doi: 10.1007/978-1-0716-1665-9_7.
Methods Mol Biol. 2021.
PMID: 34432242
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Scaffold hopping enables direct access to more potent PROTACs with in vivo activity.
Burslem GM, Bondeson DP, Crews CM.
Burslem GM, et al.
Chem Commun (Camb). 2020 Jun 23;56(50):6890-6892. doi: 10.1039/d0cc02201b.
Chem Commun (Camb). 2020.
PMID: 32519703
Free PMC article.
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