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Page 1
Variation in the SLC23A1 gene does not influence cardiometabolic outcomes to the extent expected given its association with L-ascorbic acid.
Wade KH, Forouhi NG, Cook DG, Johnson P, McConnachie A, Morris RW, Rodriguez S, Ye Z, Ebrahim S, Padmanabhan S, Watt G, Bruckdorfer KR, Wareham NJ, Whincup PH, Chanock S, Sattar N, Lawlor DA, Davey Smith G, Timpson NJ. Wade KH, et al. Am J Clin Nutr. 2015 Jan;101(1):202-9. doi: 10.3945/ajcn.114.092981. Epub 2014 Nov 19. Am J Clin Nutr. 2015. PMID: 25527764 Free PMC article.
Familial and phenotypic associations of the aldosterone Renin ratio.
Alvarez-Madrazo S, Padmanabhan S, Mayosi BM, Watkins H, Avery P, Wallace AM, Fraser R, Davies E, Keavney B, Connell JM. Alvarez-Madrazo S, et al. J Clin Endocrinol Metab. 2009 Nov;94(11):4324-33. doi: 10.1210/jc.2009-1406. Epub 2009 Oct 9. J Clin Endocrinol Metab. 2009. PMID: 19820005
Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension.
Alvarez-Madrazo S, Mackenzie SM, Davies E, Fraser R, Lee WK, Brown M, Caulfield MJ, Dominiczak AF, Farrall M, Lathrop M, Hedner T, Melander O, Munroe PB, Samani N, Stewart PM, Wahlstrand B, Webster J, Palmer CN, Padmanabhan S, Connell JM. Alvarez-Madrazo S, et al. Hypertension. 2013 Jan;61(1):232-9. doi: 10.1161/HYPERTENSIONAHA.112.200741. Epub 2012 Nov 12. Hypertension. 2013. PMID: 23150505
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.
Padmanabhan S, Melander O, Johnson T, Di Blasio AM, Lee WK, Gentilini D, Hastie CE, Menni C, Monti MC, Delles C, Laing S, Corso B, Navis G, Kwakernaak AJ, van der Harst P, Bochud M, Maillard M, Burnier M, Hedner T, Kjeldsen S, Wahlstrand B, Sjögren M, Fava C, Montagnana M, Danese E, Torffvit O, Hedblad B, Snieder H, Connell JM, Brown M, Samani NJ, Farrall M, Cesana G, Mancia G, Signorini S, Grassi G, Eyheramendy S, Wichmann HE, Laan M, Strachan DP, Sever P, Shields DC, Stanton A, Vollenweider P, Teumer A, Völzke H, Rettig R, Newton-Cheh C, Arora P, Zhang F, Soranzo N, Spector TD, Lucas G, Kathiresan S, Siscovick DS, Luan J, Loos RJ, Wareham NJ, Penninx BW, Nolte IM, McBride M, Miller WH, Nicklin SA, Baker AH, Graham D, McDonald RA, Pell JP, Sattar N, Welsh P; Global BPgen Consortium; Munroe P, Caulfield MJ, Zanchetti A, Dominiczak AF. Padmanabhan S, et al. PLoS Genet. 2010 Oct 28;6(10):e1001177. doi: 10.1371/journal.pgen.1001177. PLoS Genet. 2010. PMID: 21082022 Free PMC article.
Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants.
Timpson NJ, Forouhi NG, Brion MJ, Harbord RM, Cook DG, Johnson P, McConnachie A, Morris RW, Rodriguez S, Luan J, Ebrahim S, Padmanabhan S, Watt G, Bruckdorfer KR, Wareham NJ, Whincup PH, Chanock S, Sattar N, Lawlor DA, Davey Smith G. Timpson NJ, et al. Am J Clin Nutr. 2010 Aug;92(2):375-82. doi: 10.3945/ajcn.2010.29438. Epub 2010 Jun 2. Am J Clin Nutr. 2010. PMID: 20519558 Free PMC article.
Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide.
Turner ST, Boerwinkle E, O'Connell JR, Bailey KR, Gong Y, Chapman AB, McDonough CW, Beitelshees AL, Schwartz GL, Gums JG, Padmanabhan S, Hiltunen TP, Citterio L, Donner KM, Hedner T, Lanzani C, Melander O, Saarela J, Ripatti S, Wahlstrand B, Manunta P, Kontula K, Dominiczak AF, Cooper-DeHoff RM, Johnson JA. Turner ST, et al. Hypertension. 2013 Aug;62(2):391-7. doi: 10.1161/HYPERTENSIONAHA.111.00436. Epub 2013 Jun 10. Hypertension. 2013. PMID: 23753411 Free PMC article.