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2020 4
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Evidence, and replication thereof, that molecular-genetic and environmental risks for psychosis impact through an affective pathway.
van Os J, Pries LK, Ten Have M, de Graaf R, van Dorsselaer S, Delespaul P, Bak M, Kenis G, Lin BD, Luykx JJ, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC, Arango C, O'Donovan M, Rutten BPF, Guloksuz S. van Os J, et al. Psychol Med. 2022 Jul;52(10):1910-1922. doi: 10.1017/S0033291720003748. Epub 2020 Oct 19. Psychol Med. 2022. PMID: 33070791
Large-Scale Genomics: A Paradigm Shift in Psychiatry?
Owen MJ, O'Donovan MC. Owen MJ, et al. Biol Psychiatry. 2021 Jan 1;89(1):5-7. doi: 10.1016/j.biopsych.2020.01.017. Epub 2020 Jan 31. Biol Psychiatry. 2021. PMID: 33272362 No abstract available.
Association of Recent Stressful Life Events With Mental and Physical Health in the Context of Genomic and Exposomic Liability for Schizophrenia.
Pries LK, van Os J, Ten Have M, de Graaf R, van Dorsselaer S, Bak M, Lin BD, van Eijk KR, Kenis G, Richards A, O'Donovan MC, Luykx JJ, Rutten BPF, Guloksuz S. Pries LK, et al. JAMA Psychiatry. 2020 Dec 1;77(12):1296-1304. doi: 10.1001/jamapsychiatry.2020.2304. JAMA Psychiatry. 2020. PMID: 32805017 Free PMC article.
A replication study of JTC bias, genetic liability for psychosis and delusional ideation.
Henquet C, van Os J, Pries LK, Rauschenberg C, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran ES, Kaymak SU, Mihaljevic MM, Petrovic SS, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC, Arango C, O'Donovan M, Rutten BPF, Gülöksüz S. Henquet C, et al. Psychol Med. 2022 Jul;52(9):1777-1783. doi: 10.1017/S0033291720003578. Epub 2020 Oct 13. Psychol Med. 2022. PMID: 33046166 Free PMC article.
Examining the association between exposome score for schizophrenia and functioning in schizophrenia, siblings, and healthy controls: Results from the EUGEI study.
Erzin G, Pries LK, van Os J, Fusar-Poli L, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Andric-Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome of Psychosis (GROUP) investigators; Arango C, O'Donovan MC, Rutten BPF, Guloksuz S. Erzin G, et al. Eur Psychiatry. 2021 Mar 19;64(1):e25. doi: 10.1192/j.eurpsy.2021.19. Eur Psychiatry. 2021. PMID: 33736735 Free PMC article.
Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants.
Sanders B, D'Andrea D, Collins MO, Rees E, Steward TGJ, Zhu Y, Chapman G, Legge SE, Pardiñas AF, Harwood AJ, Gray WP, O'Donovan MC, Owen MJ, Errington AC, Blake DJ, Whitcomb DJ, Pocklington AJ, Shin E. Sanders B, et al. Nat Commun. 2022 Jan 14;13(1):27. doi: 10.1038/s41467-021-27601-0. Nat Commun. 2022. PMID: 35031607 Free PMC article.
Analysis of Diffusion Tensor Imaging Data From the UK Biobank Confirms Dosage Effect of 15q11.2 Copy Number Variation on White Matter and Shows Association With Cognition.
Silva AI, Kirov G, Kendall KM, Bracher-Smith M, Wilkinson LS, Hall J, Ulfarsson MO, Walters GB, Stefansson H, Stefansson K, Linden DEJ, Caseras X. Silva AI, et al. Biol Psychiatry. 2021 Sep 1;90(5):307-316. doi: 10.1016/j.biopsych.2021.02.969. Epub 2021 Mar 3. Biol Psychiatry. 2021. PMID: 33931204 Free PMC article.