GM55692/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1998	2
2000	3
2002	1
2003	2
2004	3
2005	2
2007	1
2008	3
2009	3
2010	5
2011	1
2012	2
2013	5
2024	0

1

Novel approaches to inhibitor design for the p110β phosphoinositide 3-kinase.

Dbouk HA, Backer JM. Dbouk HA, et al. Trends Pharmacol Sci. 2013 Mar;34(3):149-53. doi: 10.1016/j.tips.2012.12.004. Epub 2013 Feb 12. Trends Pharmacol Sci. 2013. PMID: 23411347 Free PMC article. Review.

2

The regulation of class IA PI 3-kinases by inter-subunit interactions.

Backer JM. Backer JM. Curr Top Microbiol Immunol. 2010;346:87-114. doi: 10.1007/82_2010_52. Curr Top Microbiol Immunol. 2010. PMID: 20544340 Free PMC article. Review.

3

The regulation and function of Class III PI3Ks: novel roles for Vps34.

Backer JM. Backer JM. Biochem J. 2008 Feb 15;410(1):1-17. doi: 10.1042/BJ20071427. Biochem J. 2008. PMID: 18215151 Review.

4

Phosphoinositide 3-kinases and the regulation of vesicular trafficking.

Backer JM. Backer JM. Mol Cell Biol Res Commun. 2000 Apr;3(4):193-204. doi: 10.1006/mcbr.2000.0202. Mol Cell Biol Res Commun. 2000. PMID: 10891392 Review. No abstract available.

5

Fyn phosphorylates human MAP-2c on tyrosine 67.

Zamora-Leon SP, Bresnick A, Backer JM, Shafit-Zagardo B. Zamora-Leon SP, et al. J Biol Chem. 2005 Jan 21;280(3):1962-70. doi: 10.1074/jbc.M411380200. Epub 2004 Nov 9. J Biol Chem. 2005. PMID: 15536091 Free article.

6

Phosphatidylinositol-3,4,5-trisphosphate: tool of choice for class I PI 3-kinases.

Salamon RS, Backer JM. Salamon RS, et al. Bioessays. 2013 Jul;35(7):602-11. doi: 10.1002/bies.201200176. Bioessays. 2013. PMID: 23765576 Free PMC article. Review.

7

Local signaling by the EGF receptor.

Kempiak SJ, Yip SC, Backer JM, Segall JE. Kempiak SJ, et al. J Cell Biol. 2003 Sep 1;162(5):781-7. doi: 10.1083/jcb.200303144. J Cell Biol. 2003. PMID: 12952932 Free PMC article.

8

A biochemical mechanism for the oncogenic potential of the p110beta catalytic subunit of phosphoinositide 3-kinase.

Dbouk HA, Pang H, Fiser A, Backer JM. Dbouk HA, et al. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19897-902. doi: 10.1073/pnas.1008739107. Epub 2010 Oct 28. Proc Natl Acad Sci U S A. 2010. PMID: 21030680 Free PMC article.

9

A beta version of life: p110β takes center stage.

Dbouk HA, Backer JM. Dbouk HA, et al. Oncotarget. 2010 Dec;1(8):729-733. doi: 10.18632/oncotarget.207. Oncotarget. 2010. PMID: 21321382 Free PMC article. Review.

10

Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs).

Vadas O, Dbouk HA, Shymanets A, Perisic O, Burke JE, Abi Saab WF, Khalil BD, Harteneck C, Bresnick AR, Nürnberg B, Backer JM, Williams RL. Vadas O, et al. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18862-7. doi: 10.1073/pnas.1304801110. Epub 2013 Nov 4. Proc Natl Acad Sci U S A. 2013. PMID: 24190998 Free PMC article.

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