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Year | Number of Results |
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2010 | 1 |
2013 | 3 |
2015 | 1 |
2016 | 1 |
2017 | 1 |
2024 | 0 |
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Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species.
BMC Biol. 2017 Jul 3;15(1):57. doi: 10.1186/s12915-017-0390-6.
BMC Biol. 2017.
PMID: 28673288
Free PMC article.
Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation.
Roodveldt C, Labrador-Garrido A, Gonzalez-Rey E, Lachaud CC, Guilliams T, Fernandez-Montesinos R, Benitez-Rondan A, Robledo G, Hmadcha A, Delgado M, Dobson CM, Pozo D.
Roodveldt C, et al.
PLoS One. 2013 Nov 13;8(11):e79160. doi: 10.1371/journal.pone.0079160. eCollection 2013.
PLoS One. 2013.
PMID: 24236103
Free PMC article.
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Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages.
Guilliams T, El-Turk F, Buell AK, O'Day EM, Aprile FA, Esbjörner EK, Vendruscolo M, Cremades N, Pardon E, Wyns L, Welland ME, Steyaert J, Christodoulou J, Dobson CM, De Genst E.
Guilliams T, et al.
J Mol Biol. 2013 Jul 24;425(14):2397-411. doi: 10.1016/j.jmb.2013.01.040. Epub 2013 Apr 1.
J Mol Biol. 2013.
PMID: 23557833
Free article.
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Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.
De Genst EJ, Guilliams T, Wellens J, O'Day EM, Waudby CA, Meehan S, Dumoulin M, Hsu ST, Cremades N, Verschueren KH, Pardon E, Wyns L, Steyaert J, Christodoulou J, Dobson CM.
De Genst EJ, et al.
J Mol Biol. 2010 Sep 17;402(2):326-43. doi: 10.1016/j.jmb.2010.07.001. Epub 2010 Jul 8.
J Mol Biol. 2010.
PMID: 20620148
Free article.
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α-Synuclein senses lipid packing defects and induces lateral expansion of lipids leading to membrane remodeling.
Ouberai MM, Wang J, Swann MJ, Galvagnion C, Guilliams T, Dobson CM, Welland ME.
Ouberai MM, et al.
J Biol Chem. 2013 Jul 19;288(29):20883-20895. doi: 10.1074/jbc.M113.478297. Epub 2013 Jun 5.
J Biol Chem. 2013.
PMID: 23740253
Free PMC article.
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Physical determinants of the self-replication of protein fibrils.
Šarić A, Buell AK, Meisl G, Michaels TCT, Dobson CM, Linse S, Knowles TPJ, Frenkel D.
Šarić A, et al.
Nat Phys. 2016 Sep;12(9):874-880. doi: 10.1038/nphys3828. Epub 2016 Jul 18.
Nat Phys. 2016.
PMID: 31031819
Free PMC article.
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Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation.
Chen SW, Drakulic S, Deas E, Ouberai M, Aprile FA, Arranz R, Ness S, Roodveldt C, Guilliams T, De-Genst EJ, Klenerman D, Wood NW, Knowles TP, Alfonso C, Rivas G, Abramov AY, Valpuesta JM, Dobson CM, Cremades N.
Chen SW, et al.
Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E1994-2003. doi: 10.1073/pnas.1421204112. Epub 2015 Apr 8.
Proc Natl Acad Sci U S A. 2015.
PMID: 25855634
Free PMC article.
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