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Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.
EMBO Mol Med. 2020 Apr 7;12(4):e11227. doi: 10.15252/emmm.201911227. Epub 2020 Mar 10.
EMBO Mol Med. 2020.
PMID: 32154671
Free PMC article.
Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice.
Werner G, Damme M, Schludi M, Gnörich J, Wind K, Fellerer K, Wefers B, Wurst W, Edbauer D, Brendel M, Haass C, Capell A.
Werner G, et al.
EMBO Rep. 2020 Oct 5;21(10):e50241. doi: 10.15252/embr.202050241. Epub 2020 Sep 14.
EMBO Rep. 2020.
PMID: 32929860
Free PMC article.
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Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
Ewers M, Biechele G, Suárez-Calvet M, Sacher C, Blume T, Morenas-Rodriguez E, Deming Y, Piccio L, Cruchaga C, Kleinberger G, Shaw L, Trojanowski JQ, Herms J, Dichgans M; Alzheimer's Disease Neuroimaging Initiative (ADNI); Brendel M, Haass C, Franzmeier N.
Ewers M, et al.
EMBO Mol Med. 2020 Sep 7;12(9):e12308. doi: 10.15252/emmm.202012308. Epub 2020 Aug 10.
EMBO Mol Med. 2020.
PMID: 32790063
Free PMC article.
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