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Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation.
Nixon BR, Liu B, Scellini B, Tesi C, Piroddi N, Ogut O, Solaro RJ, Ziolo MT, Janssen PM, Davis JP, Poggesi C, Biesiadecki BJ. Nixon BR, et al. Arch Biochem Biophys. 2013 Jul 1;535(1):30-8. doi: 10.1016/j.abb.2012.11.010. Epub 2012 Dec 8. Arch Biochem Biophys. 2013. PMID: 23232082 Free PMC article.
Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins.
Alves ML, Dias FAL, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT Rd, Sakthivel S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM. Alves ML, et al. Circ Cardiovasc Genet. 2014 Apr;7(2):132-143. doi: 10.1161/CIRCGENETICS.113.000324. Epub 2014 Feb 28. Circ Cardiovasc Genet. 2014. PMID: 24585742 Free PMC article.