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Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease.
Stroke. 2012 Feb;43(2):571-4. doi: 10.1161/STROKEAHA.111.625467. Epub 2011 Oct 27.
Stroke. 2012.
PMID: 22034008
Free PMC article.
A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.
McDonald DA, Shenkar R, Shi C, Stockton RA, Akers AL, Kucherlapati MH, Kucherlapati R, Brainer J, Ginsberg MH, Awad IA, Marchuk DA.
McDonald DA, et al.
Hum Mol Genet. 2011 Jan 15;20(2):211-22. doi: 10.1093/hmg/ddq433. Epub 2010 Oct 11.
Hum Mol Genet. 2011.
PMID: 20940147
Free PMC article.
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