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Page 1
Cellular senescence in bone.
Farr JN, Khosla S. Farr JN, et al. Bone. 2019 Apr;121:121-133. doi: 10.1016/j.bone.2019.01.015. Epub 2019 Jan 16. Bone. 2019. PMID: 30659978 Free PMC article. Review.
Senolytics improve physical function and increase lifespan in old age.
Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Xu M, et al. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988130 Free PMC article.
Targeting cellular senescence prevents age-related bone loss in mice.
Farr JN, Xu M, Weivoda MM, Monroe DG, Fraser DG, Onken JL, Negley BA, Sfeir JG, Ogrodnik MB, Hachfeld CM, LeBrasseur NK, Drake MT, Pignolo RJ, Pirtskhalava T, Tchkonia T, Oursler MJ, Kirkland JL, Khosla S. Farr JN, et al. Nat Med. 2017 Sep;23(9):1072-1079. doi: 10.1038/nm.4385. Epub 2017 Aug 21. Nat Med. 2017. PMID: 28825716 Free PMC article.
The role of cellular senescence in ageing and endocrine disease.
Khosla S, Farr JN, Tchkonia T, Kirkland JL. Khosla S, et al. Nat Rev Endocrinol. 2020 May;16(5):263-275. doi: 10.1038/s41574-020-0335-y. Epub 2020 Mar 11. Nat Rev Endocrinol. 2020. PMID: 32161396 Free PMC article. Review.
Osteocyte Cellular Senescence.
Farr JN, Kaur J, Doolittle ML, Khosla S. Farr JN, et al. Curr Osteoporos Rep. 2020 Oct;18(5):559-567. doi: 10.1007/s11914-020-00619-x. Curr Osteoporos Rep. 2020. PMID: 32794138 Free PMC article. Review.
Cellular senescence in age-related disorders.
Kaur J, Farr JN. Kaur J, et al. Transl Res. 2020 Dec;226:96-104. doi: 10.1016/j.trsl.2020.06.007. Epub 2020 Jun 20. Transl Res. 2020. PMID: 32569840 Free PMC article. Review.
25 results