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A tissue checkpoint regulates type 2 immunity.
Van Dyken SJ, Nussbaum JC, Lee J, Molofsky AB, Liang HE, Pollack JL, Gate RE, Haliburton GE, Ye CJ, Marson A, Erle DJ, Locksley RM. Van Dyken SJ, et al. Nat Immunol. 2016 Dec;17(12):1381-1387. doi: 10.1038/ni.3582. Epub 2016 Oct 17. Nat Immunol. 2016. PMID: 27749840 Free PMC article.
Tissue signals imprint ILC2 identity with anticipatory function.
Ricardo-Gonzalez RR, Van Dyken SJ, Schneider C, Lee J, Nussbaum JC, Liang HE, Vaka D, Eckalbar WL, Molofsky AB, Erle DJ, Locksley RM. Ricardo-Gonzalez RR, et al. Nat Immunol. 2018 Oct;19(10):1093-1099. doi: 10.1038/s41590-018-0201-4. Epub 2018 Sep 10. Nat Immunol. 2018. PMID: 30201992 Free PMC article.