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Page 1
Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK.
Neuron. 2021 Jul 21;109(14):2256-2274.e9. doi: 10.1016/j.neuron.2021.05.023. Epub 2021 Jun 16.
Neuron. 2021.
PMID: 34139149
Free PMC article.
Designer Approaches for G Protein-Coupled Receptor Modulation for Cardiovascular Disease.
Grisanti LA, Schumacher SM, Tilley DG, Koch WJ.
Grisanti LA, et al.
JACC Basic Transl Sci. 2018 Aug 28;3(4):550-562. doi: 10.1016/j.jacbts.2017.12.002. eCollection 2018 Aug.
JACC Basic Transl Sci. 2018.
PMID: 30175279
Free PMC article.
Review.
Item in Clipboard
Noncanonical Roles of G Protein-coupled Receptor Kinases in Cardiovascular Signaling.
Schumacher SM, Koch WJ.
Schumacher SM, et al.
J Cardiovasc Pharmacol. 2017 Sep;70(3):129-141. doi: 10.1097/FJC.0000000000000483.
J Cardiovasc Pharmacol. 2017.
PMID: 28328744
Free PMC article.
Review.
Item in Clipboard
The Challenge of Mentorship.
Schumacher SM.
Schumacher SM.
Circ Res. 2017 Apr 14;120(8):1232-1233. doi: 10.1161/CIRCRESAHA.117.310930.
Circ Res. 2017.
PMID: 28408449
Free PMC article.
No abstract available.
Item in Clipboard
A peptide of the amino-terminus of GRK2 induces hypertrophy and yet elicits cardioprotection after pressure overload.
Bledzka KM, Manaserh IH, Grondolsky J, Pfleger J, Roy R, Gao E, Chuprun JK, Koch WJ, Schumacher SM.
Bledzka KM, et al.
J Mol Cell Cardiol. 2021 May;154:137-153. doi: 10.1016/j.yjmcc.2021.01.004. Epub 2021 Feb 4.
J Mol Cell Cardiol. 2021.
PMID: 33548241
Free PMC article.
Item in Clipboard
A peptide of the RGS domain of GRK2 binds and inhibits Gα(q) to suppress pathological cardiac hypertrophy and dysfunction.
Schumacher SM, Gao E, Cohen M, Lieu M, Chuprun JK, Koch WJ.
Schumacher SM, et al.
Sci Signal. 2016 Mar 22;9(420):ra30. doi: 10.1126/scisignal.aae0549.
Sci Signal. 2016.
PMID: 27016525
Free PMC article.
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Pepducin ICL1-9-Mediated β2-Adrenergic Receptor-Dependent Cardiomyocyte Contractility Occurs in a Gi Protein/ROCK/PKD-Sensitive Manner.
Okyere AD, Song J, Patwa V, Carter RL, Enjamuri N, Lucchese AM, Ibetti J, de Lucia C, Schumacher SM, Koch WJ, Cheung JY, Benovic JL, Tilley DG.
Okyere AD, et al.
Cardiovasc Drugs Ther. 2023 Apr;37(2):245-256. doi: 10.1007/s10557-021-07299-4. Epub 2022 Jan 8.
Cardiovasc Drugs Ther. 2023.
PMID: 34997361
Free PMC article.
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