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Year Number of Results
2017 7
2018 6
2019 6
2020 16
2021 9
2022 5
2023 7
2024 1

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51 results

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Page 1
Mitochondrial double-stranded RNA triggers antiviral signalling in humans.
Dhir A, Dhir S, Borowski LS, Jimenez L, Teitell M, Rötig A, Crow YJ, Rice GI, Duffy D, Tamby C, Nojima T, Munnich A, Schiff M, de Almeida CR, Rehwinkel J, Dziembowski A, Szczesny RJ, Proudfoot NJ. Dhir A, et al. Nature. 2018 Aug;560(7717):238-242. doi: 10.1038/s41586-018-0363-0. Epub 2018 Jul 25. Nature. 2018. PMID: 30046113 Free PMC article.
The Z-nucleic acid sensor ZBP1 in health and disease.
Maelfait J, Rehwinkel J. Maelfait J, et al. J Exp Med. 2023 Aug 7;220(8):e20221156. doi: 10.1084/jem.20221156. Epub 2023 Jul 14. J Exp Med. 2023. PMID: 37450010 Free PMC article.
Human ZBP1 induces cell death-independent inflammatory signaling via RIPK3 and RIPK1.
Peng R, Wang CK, Wang-Kan X, Idorn M, Kjaer M, Zhou FY, Fiil BK, Timmermann F, Orozco SL, McCarthy J, Leung CS, Lu X, Bagola K, Rehwinkel J, Oberst A, Maelfait J, Paludan SR, Gyrd-Hansen M. Peng R, et al. EMBO Rep. 2022 Dec 6;23(12):e55839. doi: 10.15252/embr.202255839. Epub 2022 Oct 21. EMBO Rep. 2022. PMID: 36268590 Free PMC article.
Regulation and inhibition of the DNA sensor cGAS.
Hertzog J, Rehwinkel J. Hertzog J, et al. EMBO Rep. 2020 Dec 3;21(12):e51345. doi: 10.15252/embr.202051345. Epub 2020 Nov 5. EMBO Rep. 2020. PMID: 33155371 Free PMC article. Review.
Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Clapes T, Polyzou A, Prater P, Sagar, Morales-Hernández A, Ferrarini MG, Kehrer N, Lefkopoulos S, Bergo V, Hummel B, Obier N, Maticzka D, Bridgeman A, Herman JS, Ilik I, Klaeylé L, Rehwinkel J, McKinney-Freeman S, Backofen R, Akhtar A, Cabezas-Wallscheid N, Sawarkar R, Rebollo R, Grün D, Trompouki E. Clapes T, et al. Nat Cell Biol. 2021 Jul;23(7):704-717. doi: 10.1038/s41556-021-00707-9. Epub 2021 Jul 12. Nat Cell Biol. 2021. PMID: 34253898 Free PMC article.
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate.
Olagnier D, Farahani E, Thyrsted J, Blay-Cadanet J, Herengt A, Idorn M, Hait A, Hernaez B, Knudsen A, Iversen MB, Schilling M, Jørgensen SE, Thomsen M, Reinert LS, Lappe M, Hoang HD, Gilchrist VH, Hansen AL, Ottosen R, Nielsen CG, Møller C, van der Horst D, Peri S, Balachandran S, Huang J, Jakobsen M, Svenningsen EB, Poulsen TB, Bartsch L, Thielke AL, Luo Y, Alain T, Rehwinkel J, Alcamí A, Hiscott J, Mogensen TH, Paludan SR, Holm CK. Olagnier D, et al. Nat Commun. 2020 Oct 2;11(1):4938. doi: 10.1038/s41467-020-18764-3. Nat Commun. 2020. PMID: 33009401 Free PMC article.
Deoxyguanosine is a TLR7 agonist.
Davenne T, Bridgeman A, Rigby RE, Rehwinkel J. Davenne T, et al. Eur J Immunol. 2020 Jan;50(1):56-62. doi: 10.1002/eji.201948151. Epub 2019 Nov 14. Eur J Immunol. 2020. PMID: 31608988 Free PMC article.
51 results