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Page 1
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.
Pietras EM, Mirantes-Barbeito C, Fong S, Loeffler D, Kovtonyuk LV, Zhang S, Lakshminarasimhan R, Chin CP, Techner JM, Will B, Nerlov C, Steidl U, Manz MG, Schroeder T, Passegué E. Pietras EM, et al. Nat Cell Biol. 2016 Jun;18(6):607-18. doi: 10.1038/ncb3346. Epub 2016 Apr 25. Nat Cell Biol. 2016. PMID: 27111842 Free PMC article.
Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging.
Ho YH, Del Toro R, Rivera-Torres J, Rak J, Korn C, García-García A, Macías D, González-Gómez C, Del Monte A, Wittner M, Waller AK, Foster HR, López-Otín C, Johnson RS, Nerlov C, Ghevaert C, Vainchenker W, Louache F, Andrés V, Méndez-Ferrer S. Ho YH, et al. Cell Stem Cell. 2019 Sep 5;25(3):407-418.e6. doi: 10.1016/j.stem.2019.06.007. Epub 2019 Jul 11. Cell Stem Cell. 2019. PMID: 31303548 Free PMC article.
Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion.
Wojtowicz EE, Mistry JJ, Uzun V, Hellmich C, Scoones A, Chin DW, Kettyle LM, Grasso F, Lord AM, Wright DJ, Etherington GJ, Woll PS, Belderbos ME, Bowles KM, Nerlov C, Haerty W, Bystrykh LV, Jacobsen SEW, Rushworth SA, Macaulay IC. Wojtowicz EE, et al. Genome Biol. 2023 Jun 27;24(1):152. doi: 10.1186/s13059-023-02976-z. Genome Biol. 2023. PMID: 37370129 Free PMC article.
Inflammatory signals directly instruct PU.1 in HSCs via TNF.
Etzrodt M, Ahmed N, Hoppe PS, Loeffler D, Skylaki S, Hilsenbeck O, Kokkaliaris KD, Kaltenbach HM, Stelling J, Nerlov C, Schroeder T. Etzrodt M, et al. Blood. 2019 Feb 21;133(8):816-819. doi: 10.1182/blood-2018-02-832998. Epub 2018 Oct 9. Blood. 2019. PMID: 30301719 Free article.
Direct role of FLT3 in regulation of early lymphoid progenitors.
Zriwil A, Böiers C, Kristiansen TA, Wittmann L, Yuan J, Nerlov C, Sitnicka E, Jacobsen SEW. Zriwil A, et al. Br J Haematol. 2018 Nov;183(4):588-600. doi: 10.1111/bjh.15578. Epub 2018 Sep 14. Br J Haematol. 2018. PMID: 30596405 Free PMC article.
38 results