MC_UU_12022/9/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2015	4
2016	1
2017	1
2018	3
2019	2
2020	4
2021	7
2022	2
2023	2
2024	0

1

Mutant clones in normal epithelium outcompete and eliminate emerging tumours.

Colom B, Herms A, Hall MWJ, Dentro SC, King C, Sood RK, Alcolea MP, Piedrafita G, Fernandez-Antoran D, Ong SH, Fowler JC, Mahbubani KT, Saeb-Parsy K, Gerstung M, Hall BA, Jones PH. Colom B, et al. Nature. 2021 Oct;598(7881):510-514. doi: 10.1038/s41586-021-03965-7. Epub 2021 Oct 13. Nature. 2021. PMID: 34646013 Free PMC article.

2

p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition.

Murai K, Dentro S, Ong SH, Sood R, Fernandez-Antoran D, Herms A, Kostiou V, Abnizova I, Hall BA, Gerstung M, Jones PH. Murai K, et al. Nat Commun. 2022 Oct 20;13(1):6206. doi: 10.1038/s41467-022-33945-y. Nat Commun. 2022. PMID: 36266286 Free PMC article.

3

Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium.

Colom B, Alcolea MP, Piedrafita G, Hall MWJ, Wabik A, Dentro SC, Fowler JC, Herms A, King C, Ong SH, Sood RK, Gerstung M, Martincorena I, Hall BA, Jones PH. Colom B, et al. Nat Genet. 2020 Jun;52(6):604-614. doi: 10.1038/s41588-020-0624-3. Epub 2020 May 18. Nat Genet. 2020. PMID: 32424351 Free PMC article.

4

Methods for analysing lineage tracing datasets.

Kostiou V, Zhang H, Hall MWJ, Jones PH, Hall BA. Kostiou V, et al. R Soc Open Sci. 2021 May 5;8(5):202231. doi: 10.1098/rsos.202231. R Soc Open Sci. 2021. PMID: 34035949 Free PMC article.

5

Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.

Abby E, Dentro SC, Hall MWJ, Fowler JC, Ong SH, Sood R, Herms A, Piedrafita G, Abnizova I, Siebel CW, Gerstung M, Hall BA, Jones PH. Abby E, et al. Nat Genet. 2023 Feb;55(2):232-245. doi: 10.1038/s41588-022-01280-z. Epub 2023 Jan 19. Nat Genet. 2023. PMID: 36658434 Free PMC article.

6

Cellular survival over genomic perfection.

Nik-Zainal S, Hall BA. Nik-Zainal S, et al. Science. 2019 Nov 15;366(6467):802-803. doi: 10.1126/science.aax8046. Science. 2019. PMID: 31727818 Free PMC article. No abstract available.

7

Tumor-induced stromal reprogramming drives lymph node transformation.

Riedel A, Shorthouse D, Haas L, Hall BA, Shields J. Riedel A, et al. Nat Immunol. 2016 Sep;17(9):1118-27. doi: 10.1038/ni.3492. Epub 2016 Jul 11. Nat Immunol. 2016. PMID: 27400148 Free PMC article.

8

Constructing and Analyzing Computational Models of Cell Signaling with BioModelAnalyzer.

Hall BA, Fisher J. Hall BA, et al. Curr Protoc Bioinformatics. 2020 Mar;69(1):e95. doi: 10.1002/cpbi.95. Curr Protoc Bioinformatics. 2020. PMID: 32078258

9

Computational Saturation Screen Reveals the Landscape of Mutations in Human Fumarate Hydratase.

Shorthouse D, Hall MWJ, Hall BA. Shorthouse D, et al. J Chem Inf Model. 2021 Apr 26;61(4):1970-1980. doi: 10.1021/acs.jcim.1c00063. Epub 2021 Apr 13. J Chem Inf Model. 2021. PMID: 33848143

10

A toolbox for discrete modelling of cell signalling dynamics.

Paterson YZ, Shorthouse D, Pleijzier MW, Piterman N, Bendtsen C, Hall BA, Fisher J. Paterson YZ, et al. Integr Biol (Camb). 2018 Jun 18;10(6):370-382. doi: 10.1039/c8ib00026c. Integr Biol (Camb). 2018. PMID: 29855020

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