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GEFs: Dual regulation of Rac1 signaling.
Marei H, Malliri A. Marei H, et al. Small GTPases. 2017 Apr 3;8(2):90-99. doi: 10.1080/21541248.2016.1202635. Epub 2016 Jun 17. Small GTPases. 2017. PMID: 27314616 Free PMC article. Review.
Deregulation of Rho GTPases in cancer.
Porter AP, Papaioannou A, Malliri A. Porter AP, et al. Small GTPases. 2016 Jul 2;7(3):123-38. doi: 10.1080/21541248.2016.1173767. Epub 2016 Apr 22. Small GTPases. 2016. PMID: 27104658 Free PMC article. Review.
TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells.
Diamantopoulou Z, White G, Fadlullah MZH, Dreger M, Pickering K, Maltas J, Ashton G, MacLeod R, Baillie GS, Kouskoff V, Lacaud G, Murray GI, Sansom OJ, Hurlstone AFL, Malliri A. Diamantopoulou Z, et al. Cancer Cell. 2017 May 8;31(5):621-634.e6. doi: 10.1016/j.ccell.2017.03.007. Epub 2017 Apr 13. Cancer Cell. 2017. PMID: 28416184 Free PMC article.
HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.
Myant KB, Cammareri P, Hodder MC, Wills J, Von Kriegsheim A, Győrffy B, Rashid M, Polo S, Maspero E, Vaughan L, Gurung B, Barry E, Malliri A, Camargo F, Adams DJ, Iavarone A, Lasorella A, Sansom OJ. Myant KB, et al. EMBO Mol Med. 2017 Feb;9(2):181-197. doi: 10.15252/emmm.201606684. EMBO Mol Med. 2017. PMID: 28003334 Free PMC article.