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Page 1
Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes.
Dunne JL, Richardson SJ, Atkinson MA, Craig ME, Dahl-Jørgensen K, Flodström-Tullberg M, Hyöty H, Insel RA, Lernmark Å, Lloyd RE, Morgan NG, Pugliese A. Dunne JL, et al. Diabetologia. 2019 May;62(5):744-753. doi: 10.1007/s00125-019-4811-7. Epub 2019 Jan 23. Diabetologia. 2019. PMID: 30675626 Free PMC article. Review.
Detection of Antiviral Tissue Responses and Increased Cell Stress in the Pancreatic Islets of Newly Diagnosed Type 1 Diabetes Patients: Results From the DiViD Study.
Krogvold L, Leete P, Mynarek IM, Russell MA, Gerling IC, Lenchik NI, Mathews C, Richardson SJ, Morgan NG, Dahl-Jørgensen K. Krogvold L, et al. Front Endocrinol (Lausanne). 2022 Jul 26;13:881997. doi: 10.3389/fendo.2022.881997. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35957810 Free PMC article.
Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage.
Sioofy-Khojine AB, Richardson SJ, Locke JM, Oikarinen S, Nurminen N, Laine AP, Downes K, Lempainen J, Todd JA, Veijola R, Ilonen J, Knip M, Morgan NG, Hyöty H, Peakman M, Eichmann M. Sioofy-Khojine AB, et al. Diabetologia. 2022 Oct;65(10):1701-1709. doi: 10.1007/s00125-022-05753-y. Epub 2022 Jul 22. Diabetologia. 2022. PMID: 35867130 Free PMC article.
PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction.
Colli ML, Hill JLE, Marroquí L, Chaffey J, Dos Santos RS, Leete P, Coomans de Brachène A, Paula FMM, Op de Beeck A, Castela A, Marselli L, Krogvold L, Dahl-Jorgensen K, Marchetti P, Morgan NG, Richardson SJ, Eizirik DL. Colli ML, et al. EBioMedicine. 2018 Oct;36:367-375. doi: 10.1016/j.ebiom.2018.09.040. Epub 2018 Sep 27. EBioMedicine. 2018. PMID: 30269996 Free PMC article.
20 results