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Year Number of Results
2018 1
2019 4
2020 6
2021 4
2022 3
2023 6
2024 0

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Page 1
Using human genetics to understand the disease impacts of testosterone in men and women.
Ruth KS, Day FR, Tyrrell J, Thompson DJ, Wood AR, Mahajan A, Beaumont RN, Wittemans L, Martin S, Busch AS, Erzurumluoglu AM, Hollis B, O'Mara TA; Endometrial Cancer Association Consortium; McCarthy MI, Langenberg C, Easton DF, Wareham NJ, Burgess S, Murray A, Ong KK, Frayling TM, Perry JRB. Ruth KS, et al. Nat Med. 2020 Feb;26(2):252-258. doi: 10.1038/s41591-020-0751-5. Epub 2020 Feb 10. Nat Med. 2020. PMID: 32042192 Free PMC article.
Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study.
Budu-Aggrey A, Brumpton B, Tyrrell J, Watkins S, Modalsli EH, Celis-Morales C, Ferguson LD, Vie GÅ, Palmer T, Fritsche LG, Løset M, Nielsen JB, Zhou W, Tsoi LC, Wood AR, Jones SE, Beaumont R, Saunes M, Romundstad PR, Siebert S, McInnes IB, Elder JT, Davey Smith G, Frayling TM, Åsvold BO, Brown SJ, Sattar N, Paternoster L. Budu-Aggrey A, et al. PLoS Med. 2019 Jan 31;16(1):e1002739. doi: 10.1371/journal.pmed.1002739. eCollection 2019 Jan. PLoS Med. 2019. PMID: 30703100 Free PMC article.
Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation.
Martin S, Tyrrell J, Thomas EL, Bown MJ, Wood AR, Beaumont RN, Tsoi LC, Stuart PE, Elder JT, Law P, Houlston R, Kabrhel C, Papadimitriou N, Gunter MJ, Bull CJ, Bell JA, Vincent EE, Sattar N, Dunlop MG, Tomlinson IPM, Lindström S; INVENT consortium; Bell JD, Frayling TM, Yaghootkar H. Martin S, et al. Elife. 2022 Jan 25;11:e72452. doi: 10.7554/eLife.72452. Elife. 2022. PMID: 35074047 Free PMC article.
Methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology: A systematic literature review.
Power GM, Sanderson E, Pagoni P, Fraser A, Morris T, Prince C, Frayling TM, Heron J, Richardson TG, Richmond R, Tyrrell J, Warrington N, Davey Smith G, Howe LD, Tilling KM. Power GM, et al. Eur J Epidemiol. 2023 Nov 8. doi: 10.1007/s10654-023-01032-1. Online ahead of print. Eur J Epidemiol. 2023. PMID: 37938447 Review.
Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile.
Heald AH, Martin S, Fachim H, Green HD, Young KG, Malipatil N, Siddals K, Cortes G, Tyrrell J, Wood AR, Beaumont RN, Frayling TM, Donn R, Narayanan RP, Ollier W, Gibson M, Yaghootkar H. Heald AH, et al. Diabet Med. 2021 Sep;38(9):e14531. doi: 10.1111/dme.14531. Epub 2021 Feb 11. Diabet Med. 2021. PMID: 33501652
23 results