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2021 4
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Multi-omics identify falling LRRC15 as a COVID-19 severity marker and persistent pro-thrombotic signals in convalescence.
Gisby JS, Buang NB, Papadaki A, Clarke CL, Malik TH, Medjeral-Thomas N, Pinheiro D, Mortimer PM, Lewis S, Sandhu E, McAdoo SP, Prendecki MF, Willicombe M, Pickering MC, Botto M, Thomas DC, Peters JE. Gisby JS, et al. Nat Commun. 2022 Dec 15;13(1):7775. doi: 10.1038/s41467-022-35454-4. Nat Commun. 2022. PMID: 36522333 Free PMC article.
Protease inhibitor plasma concentrations associate with COVID-19 infection.
Medjeral-Thomas NR, Troldborg A, Hansen AG, Pihl R, Clarke CL, Peters JE, Thomas DC, Willicombe M, Palarasah Y, Botto M, Pickering MC, Thiel S. Medjeral-Thomas NR, et al. Oxf Open Immunol. 2021 Jul 7;2(1):iqab014. doi: 10.1093/oxfimm/iqab014. eCollection 2021. Oxf Open Immunol. 2021. PMID: 34458849 Free PMC article.
Plasma Lectin Pathway Complement Proteins in Patients With COVID-19 and Renal Disease.
Medjeral-Thomas NR, Troldborg A, Hansen AG, Gisby J, Clarke CL, Prendecki M, McAdoo SP, Sandhu E, Lightstone L, Thomas DC, Willicombe M, Botto M, Peters JE, Pickering MC, Thiel S. Medjeral-Thomas NR, et al. Front Immunol. 2021 Apr 29;12:671052. doi: 10.3389/fimmu.2021.671052. eCollection 2021. Front Immunol. 2021. PMID: 33995410 Free PMC article. Clinical Trial.
Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways of individuals with ongoing post-COVID-19 respiratory disease.
Vijayakumar B, Boustani K, Ogger PP, Papadaki A, Tonkin J, Orton CM, Ghai P, Suveizdyte K, Hewitt RJ, Desai SR, Devaraj A, Snelgrove RJ, Molyneaux PL, Garner JL, Peters JE, Shah PL, Lloyd CM, Harker JA. Vijayakumar B, et al. Immunity. 2022 Mar 8;55(3):542-556.e5. doi: 10.1016/j.immuni.2022.01.017. Epub 2022 Jan 26. Immunity. 2022. PMID: 35151371 Free PMC article.
Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19.
Klaric L, Gisby JS, Papadaki A, Muckian MD, Macdonald-Dunlop E, Zhao JH, Tokolyi A, Persyn E, Pairo-Castineira E, Morris AP, Kalnapenkis A, Richmond A, Landini A, Hedman ÅK, Prins B, Zanetti D, Wheeler E, Kooperberg C, Yao C, Petrie JR, Fu J, Folkersen L, Walker M, Magnusson M, Eriksson N, Mattsson-Carlgren N, Timmers PRHJ, Hwang SJ, Enroth S, Gustafsson S, Vosa U, Chen Y, Siegbahn A, Reiner A, Johansson Å, Thorand B, Gigante B, Hayward C, Herder C, Gieger C, Langenberg C, Levy D, Zhernakova DV, Smith JG, Campbell H, Sundstrom J, Danesh J, Michaëlsson K, Suhre K, Lind L, Wallentin L, Padyukov L, Landén M, Wareham NJ, Göteson A, Hansson O, Eriksson P, Strawbridge RJ, Assimes TL, Esko T, Gyllensten U, Baillie JK, Paul DS, Joshi PK, Butterworth AS, Mälarstig A, Pirastu N, Wilson JF, Peters JE. Klaric L, et al. medRxiv [Preprint]. 2021 Apr 7:2021.04.01.21254789. doi: 10.1101/2021.04.01.21254789. medRxiv. 2021. PMID: 33851187 Free PMC article. Preprint.
Longitudinal proteomic profiling of dialysis patients with COVID-19 reveals markers of severity and predictors of death.
Gisby J, Clarke CL, Medjeral-Thomas N, Malik TH, Papadaki A, Mortimer PM, Buang NB, Lewis S, Pereira M, Toulza F, Fagnano E, Mawhin MA, Dutton EE, Tapeng L, Richard AC, Kirk PD, Behmoaras J, Sandhu E, McAdoo SP, Prendecki MF, Pickering MC, Botto M, Willicombe M, Thomas DC, Peters JE. Gisby J, et al. Elife. 2021 Mar 11;10:e64827. doi: 10.7554/eLife.64827. Elife. 2021. PMID: 33704068 Free PMC article.