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ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation.
Nat Cell Biol. 2008 Feb;10(2):138-48. doi: 10.1038/ncb1676. Epub 2008 Jan 20.
Nat Cell Biol. 2008.
PMID: 18204439
Free PMC article.
Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.
Yen CJ, Izzo JG, Lee DF, Guha S, Wei Y, Wu TT, Chen CT, Kuo HP, Hsu JM, Sun HL, Chou CK, Buttar NS, Wang KK, Huang P, Ajani J, Hung MC.
Yen CJ, et al.
Cancer Res. 2008 Apr 15;68(8):2632-40. doi: 10.1158/0008-5472.CAN-07-5460.
Cancer Res. 2008.
PMID: 18413730
Free PMC article.
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Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers.
Wei Y, Xia W, Zhang Z, Liu J, Wang H, Adsay NV, Albarracin C, Yu D, Abbruzzese JL, Mills GB, Bast RC Jr, Hortobagyi GN, Hung MC.
Wei Y, et al.
Mol Carcinog. 2008 Sep;47(9):701-6. doi: 10.1002/mc.20413.
Mol Carcinog. 2008.
PMID: 18176935
Free PMC article.
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