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Page 1
Mechanisms and inhibition of Porcupine-mediated Wnt acylation.
Liu Y, Qi X, Donnelly L, Elghobashi-Meinhardt N, Long T, Zhou RW, Sun Y, Wang B, Li X. Liu Y, et al. Nature. 2022 Jul;607(7920):816-822. doi: 10.1038/s41586-022-04952-2. Epub 2022 Jul 13. Nature. 2022. PMID: 35831507 Free PMC article.
Structure and mechanism of human cystine exporter cystinosin.
Guo X, Schmiege P, Assafa TE, Wang R, Xu Y, Donnelly L, Fine M, Ni X, Jiang J, Millhauser G, Feng L, Li X. Guo X, et al. Cell. 2022 Sep 29;185(20):3739-3752.e18. doi: 10.1016/j.cell.2022.08.020. Epub 2022 Sep 15. Cell. 2022. PMID: 36113465 Free PMC article.
PCSK9: From Nature's Loss to Patient's Gain.
Hobbs HH, Cohen JC, Horton JD. Hobbs HH, et al. Circulation. 2024 Jan 16;149(3):171-173. doi: 10.1161/CIRCULATIONAHA.123.064498. Epub 2024 Jan 16. Circulation. 2024. PMID: 38227713 Free PMC article. No abstract available.
The ubiquitin E3 ligase BFAR promotes degradation of PNPLA3.
Das A, Cheng H, Wang Y, Kinch LN, Liang G, Hong S, Hobbs HH, Cohen JC. Das A, et al. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2312291121. doi: 10.1073/pnas.2312291121. Epub 2024 Jan 31. Proc Natl Acad Sci U S A. 2024. PMID: 38294943 Free PMC article.
25-Hydroxycholesterol exacerbates vascular leak during acute lung injury.
Madenspacher JH, Morrell ED, McDonald JG, Thompson BM, Li Y, Birukov KG, Birukova AA, Stapleton RD, Alejo A, Karmaus PW, Meacham JM, Rai P, Mikacenic C, Wurfel MM, Fessler MB. Madenspacher JH, et al. JCI Insight. 2023 Apr 10;8(7):e155448. doi: 10.1172/jci.insight.155448. JCI Insight. 2023. PMID: 36821369 Free PMC article.
25 results