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Page 1
Frataxin deficiency promotes endothelial senescence in pulmonary hypertension.
Culley MK, Zhao J, Tai YY, Tang Y, Perk D, Negi V, Yu Q, Woodcock CC, Handen A, Speyer G, Kim S, Lai YC, Satoh T, Watson AM, Aaraj YA, Sembrat J, Rojas M, Goncharov D, Goncharova EA, Khan OF, Anderson DG, Dahlman JE, Gurkar AU, Lafyatis R, Fayyaz AU, Redfield MM, Gladwin MT, Rabinovitch M, Gu M, Bertero T, Chan SY. Culley MK, et al. J Clin Invest. 2021 Jun 1;131(11):e136459. doi: 10.1172/JCI136459. J Clin Invest. 2021. PMID: 33905372 Free PMC article.
Nuclear Genomic Instability and Aging.
Niedernhofer LJ, Gurkar AU, Wang Y, Vijg J, Hoeijmakers JHJ, Robbins PD. Niedernhofer LJ, et al. Annu Rev Biochem. 2018 Jun 20;87:295-322. doi: 10.1146/annurev-biochem-062917-012239. Annu Rev Biochem. 2018. PMID: 29925262 Review.
Cellular Senescence: The Trojan Horse in Chronic Lung Diseases.
Hamsanathan S, Alder JK, Sellares J, Rojas M, Gurkar AU, Mora AL. Hamsanathan S, et al. Am J Respir Cell Mol Biol. 2019 Jul;61(1):21-30. doi: 10.1165/rcmb.2018-0410TR. Am J Respir Cell Mol Biol. 2019. PMID: 30965013 Free PMC article. Review.
Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy.
Henpita C, Vyas R, Healy CL, Kieu TL, Gurkar AU, Yousefzadeh MJ, Cui Y, Lu A, Angelini LA, O'Kelly RD, McGowan SJ, Chandrasekhar S, Vanderpool RR, Hennessy-Wack D, Ross MA, Bachman TN, McTiernan C, Pillai SPS, Ladiges W, Lavasani M, Huard J, Beer-Stolz D, St Croix CM, Watkins SC, Robbins PD, Mora AL, Kelley EE, Wang Y, O'Connell TD, Niedernhofer LJ. Henpita C, et al. Aging Cell. 2023 Apr;22(4):e13782. doi: 10.1111/acel.13782. Epub 2023 Feb 3. Aging Cell. 2023. PMID: 36734200 Free PMC article.
ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation.
Czerwińska J, Nowak M, Wojtczak P, Dziuban-Lech D, Cieśla JM, Kołata D, Gajewska B, Barańczyk-Kuźma A, Robinson AR, Shane HL, Gregg SQ, Rigatti LH, Yousefzadeh MJ, Gurkar AU, McGowan SJ, Kosicki K, Bednarek M, Zarakowska E, Gackowski D, Oliński R, Speina E, Niedernhofer LJ, Tudek B. Czerwińska J, et al. Free Radic Biol Med. 2018 Aug 20;124:79-96. doi: 10.1016/j.freeradbiomed.2018.05.088. Epub 2018 Jun 1. Free Radic Biol Med. 2018. PMID: 29860127 Free PMC article.
Quantitative Analysis of Cellular Senescence in Culture and In Vivo.
Zhao J, Fuhrmann-Stroissnigg H, Gurkar AU, Flores RR, Dorronsoro A, Stolz DB, St Croix CM, Niedernhofer LJ, Robbins PD. Zhao J, et al. Curr Protoc Cytom. 2017 Jan 5;79:9.51.1-9.51.25. doi: 10.1002/cpcy.16. Curr Protoc Cytom. 2017. PMID: 28055114
18 results