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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2017 | 1 |
2018 | 1 |
2021 | 1 |
2022 | 2 |
2023 | 1 |
2024 | 0 |
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A CRISPR-drug perturbational map for identifying compounds to combine with commonly used chemotherapeutics.
Nat Commun. 2023 Nov 13;14(1):7332. doi: 10.1038/s41467-023-43134-0.
Nat Commun. 2023.
PMID: 37957169
Free PMC article.
The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.
Pan M, Wright WC, Chapple RH, Zubair A, Sandhu M, Batchelder JE, Huddle BC, Low J, Blankenship KB, Wang Y, Gordon B, Archer P, Brady SW, Natarajan S, Posgai MJ, Schuetz J, Miller D, Kalathur R, Chen S, Connelly JP, Babu MM, Dyer MA, Pruett-Miller SM, Freeman BB 3rd, Chen T, Godley LA, Blanchard SC, Stewart E, Easton J, Geeleher P.
Pan M, et al.
Nat Commun. 2021 Nov 9;12(1):6468. doi: 10.1038/s41467-021-26640-x.
Nat Commun. 2021.
PMID: 34753908
Free PMC article.
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Random-effects meta-analysis of effect sizes as a unified framework for gene set analysis.
Makrooni MA, O'Shea D, Geeleher P, Seoighe C.
Makrooni MA, et al.
PLoS Comput Biol. 2022 Oct 5;18(10):e1010278. doi: 10.1371/journal.pcbi.1010278. eCollection 2022 Oct.
PLoS Comput Biol. 2022.
PMID: 36197939
Free PMC article.
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Cell type identification in spatial transcriptomics data can be improved by leveraging cell-type-informative paired tissue images using a Bayesian probabilistic model.
Zubair A, Chapple RH, Natarajan S, Wright WC, Pan M, Lee HM, Tillman H, Easton J, Geeleher P.
Zubair A, et al.
Nucleic Acids Res. 2022 Aug 12;50(14):e80. doi: 10.1093/nar/gkac320.
Nucleic Acids Res. 2022.
PMID: 35536287
Free PMC article.
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Discovering novel pharmacogenomic biomarkers by imputing drug response in cancer patients from large genomics studies.
Geeleher P, Zhang Z, Wang F, Gruener RF, Nath A, Morrison G, Bhutra S, Grossman RL, Huang RS.
Geeleher P, et al.
Genome Res. 2017 Oct;27(10):1743-1751. doi: 10.1101/gr.221077.117. Epub 2017 Aug 28.
Genome Res. 2017.
PMID: 28847918
Free PMC article.
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Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity.
Geeleher P, Nath A, Wang F, Zhang Z, Barbeira AN, Fessler J, Grossman RL, Seoighe C, Stephanie Huang R.
Geeleher P, et al.
Genome Biol. 2018 Sep 11;19(1):130. doi: 10.1186/s13059-018-1507-0.
Genome Biol. 2018.
PMID: 30205839
Free PMC article.
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