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Telomeres and sirtuins: at the end we meet again.
Amano H, Sahin E. Amano H, et al. Mol Cell Oncol. 2019 Jul 7;6(5):e1632613. doi: 10.1080/23723556.2019.1632613. eCollection 2019. Mol Cell Oncol. 2019. PMID: 31528700 Free PMC article.
Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease.
Amano H, Chaudhury A, Rodriguez-Aguayo C, Lu L, Akhanov V, Catic A, Popov YV, Verdin E, Johnson H, Stossi F, Sinclair DA, Nakamaru-Ogiso E, Lopez-Berestein G, Chang JT, Neilson JR, Meeker A, Finegold M, Baur JA, Sahin E. Amano H, et al. Cell Metab. 2019 Jun 4;29(6):1274-1290.e9. doi: 10.1016/j.cmet.2019.03.001. Epub 2019 Mar 28. Cell Metab. 2019. PMID: 30930169 Free PMC article.
A chemical chaperone improves muscle function in mice with a RyR1 mutation.
Lee CS, Hanna AD, Wang H, Dagnino-Acosta A, Joshi AD, Knoblauch M, Xia Y, Georgiou DK, Xu J, Long C, Amano H, Reynolds C, Dong K, Martin JC, Lagor WR, Rodney GG, Sahin E, Sewry C, Hamilton SL. Lee CS, et al. Nat Commun. 2017 Mar 24;8:14659. doi: 10.1038/ncomms14659. Nat Commun. 2017. PMID: 28337975 Free PMC article.