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SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms.
Szeto IYY, Chu DKH, Chen P, Chu KC, Au TYK, Leung KKH, Huang YH, Wynn SL, Mak ACY, Chan YS, Chan WY, Jauch R, Fritzsch B, Sham MH, Lovell-Badge R, Cheah KSE. Szeto IYY, et al. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2122121119. doi: 10.1073/pnas.2122121119. Epub 2022 Nov 7. Proc Natl Acad Sci U S A. 2022. PMID: 36343245 Free PMC article.
Disruption of mitochondria-sarcoplasmic reticulum microdomain connectomics contributes to sinus node dysfunction in heart failure.
Ren L, Gopireddy RR, Perkins G, Zhang H, Timofeyev V, Lyu Y, Diloretto DA, Trinh P, Sirish P, Overton JL, Xu W, Grainger N, Xiang YK, Dedkova EN, Zhang XD, Yamoah EN, Navedo MF, Thai PN, Chiamvimonvat N. Ren L, et al. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2206708119. doi: 10.1073/pnas.2206708119. Epub 2022 Aug 31. Proc Natl Acad Sci U S A. 2022. PMID: 36044551 Free PMC article.
Using Sox2 to alleviate the hallmarks of age-related hearing loss.
Yamoah EN, Li M, Shah A, Elliott KL, Cheah K, Xu PX, Phillips S, Young SM Jr, Eberl DF, Fritzsch B. Yamoah EN, et al. Ageing Res Rev. 2020 May;59:101042. doi: 10.1016/j.arr.2020.101042. Epub 2020 Mar 12. Ageing Res Rev. 2020. PMID: 32173536 Free PMC article. Review.
The Piezo channel is central to the mechano-sensitive channel complex in the mammalian inner ear.
Lee JH, Perez-Flores MC, Park S, Kim HJ, Chen Y, Kang M, Kersigo J, Choi J, Thai PN, Woltz R, Perez-Flores DC, Perkins G, Sihn CR, Trinh P, Zhang XD, Sirish P, Dong Y, Feng WW, Pessah IN, Dixon RE, Sokolowski B, Fritzsch B, Chiamvimonvat N, Yamoah EN. Lee JH, et al. Res Sq [Preprint]. 2023 Jul 12:rs.3.rs-2287052. doi: 10.21203/rs.3.rs-2287052/v1. Res Sq. 2023. PMID: 37502846 Free PMC article. Updated. Preprint.
38 results