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Depletion of antibiotic targets has widely varying effects on growth.
Wei JR, Krishnamoorthy V, Murphy K, Kim JH, Schnappinger D, Alber T, Sassetti CM, Rhee KY, Rubin EJ. Wei JR, et al. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4176-81. doi: 10.1073/pnas.1018301108. Epub 2011 Feb 22. Proc Natl Acad Sci U S A. 2011. PMID: 21368134 Free PMC article.
A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria.
Gee CL, Papavinasasundaram KG, Blair SR, Baer CE, Falick AM, King DS, Griffin JE, Venghatakrishnan H, Zukauskas A, Wei JR, Dhiman RK, Crick DC, Rubin EJ, Sassetti CM, Alber T. Gee CL, et al. Sci Signal. 2012 Jan 24;5(208):ra7. doi: 10.1126/scisignal.2002525. Sci Signal. 2012. PMID: 22275220 Free PMC article.