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Context Matters: Contribution of Specific DNA Adducts to the Genotoxic Properties of the Tobacco-Specific Nitrosamine NNK.
Chem Res Toxicol. 2017 Jan 17;30(1):420-433. doi: 10.1021/acs.chemrestox.6b00386. Epub 2016 Dec 8.
Chem Res Toxicol. 2017.
PMID: 28092943
Free PMC article.
Review.
Role of aldehydes in the toxic and mutagenic effects of nitrosamines.
Peterson LA, Urban AM, Vu CC, Cummings ME, Brown LC, Warmka JK, Li L, Wattenberg EV, Patel Y, Stram DO, Pegg AE.
Peterson LA, et al.
Chem Res Toxicol. 2013 Oct 21;26(10):1464-73. doi: 10.1021/tx400196j. Epub 2013 Sep 25.
Chem Res Toxicol. 2013.
PMID: 24066836
Free PMC article.
Item in Clipboard
Flipping of alkylated DNA damage bridges base and nucleotide excision repair.
Tubbs JL, Latypov V, Kanugula S, Butt A, Melikishvili M, Kraehenbuehl R, Fleck O, Marriott A, Watson AJ, Verbeek B, McGown G, Thorncroft M, Santibanez-Koref MF, Millington C, Arvai AS, Kroeger MD, Peterson LA, Williams DM, Fried MG, Margison GP, Pegg AE, Tainer JA.
Tubbs JL, et al.
Nature. 2009 Jun 11;459(7248):808-13. doi: 10.1038/nature08076.
Nature. 2009.
PMID: 19516334
Free PMC article.
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Formation, repair, and genotoxic properties of bulky DNA adducts formed from tobacco-specific nitrosamines.
Peterson LA.
Peterson LA.
J Nucleic Acids. 2010 Sep 5;2010:284935. doi: 10.4061/2010/284935.
J Nucleic Acids. 2010.
PMID: 20871819
Free PMC article.
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The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
Thomson NM, Kenney PM, Peterson LA.
Thomson NM, et al.
Chem Res Toxicol. 2003 Jan;16(1):1-6. doi: 10.1021/tx025585k.
Chem Res Toxicol. 2003.
PMID: 12693024
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Decomposition of S-nitrosocysteine via S- to N-transnitrosation.
Peterson LA, Wagener T, Sies H, Stahl W.
Peterson LA, et al.
Chem Res Toxicol. 2007 May;20(5):721-3. doi: 10.1021/tx700095u. Epub 2007 Apr 18.
Chem Res Toxicol. 2007.
PMID: 17439249
Free PMC article.
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Differences in the rate of repair of O6-alkylguanines in different sequence contexts by O6-alkylguanine-DNA alkyltransferase.
Coulter R, Blandino M, Tomlinson JM, Pauly GT, Krajewska M, Moschel RC, Peterson LA, Pegg AE, Spratt TE.
Coulter R, et al.
Chem Res Toxicol. 2007 Dec;20(12):1966-71. doi: 10.1021/tx700271j. Epub 2007 Nov 1.
Chem Res Toxicol. 2007.
PMID: 17975884
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