R01 CA167677/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2012	6
2013	3
2014	4
2015	6
2016	3
2017	8
2018	6
2019	2
2021	1
2024	0

1

The Pin1-CaMKII-AMPA Receptor Axis Regulates Epileptic Susceptibility.

Hou X, Yang F, Li A, Zhao D, Ma N, Chen L, Lin S, Lin Y, Wang L, Yan X, Zheng M, Lee TH, Zhou XZ, Lu KP, Liu H. Hou X, et al. Cereb Cortex. 2021 May 10;31(6):3082-3095. doi: 10.1093/cercor/bhab004. Cereb Cortex. 2021. PMID: 33569579 Free PMC article.

2

Function and regulation of tau conformations in the development and treatment of traumatic brain injury and neurodegeneration.

Albayram O, Herbert MK, Kondo A, Tsai CY, Baxley S, Lian X, Hansen M, Zhou XZ, Lu KP. Albayram O, et al. Cell Biosci. 2016 Dec 5;6:59. doi: 10.1186/s13578-016-0124-4. eCollection 2016. Cell Biosci. 2016. PMID: 27980715 Free PMC article. Review.

3

Pin1-Targeted Therapy for Systemic Lupus Erythematosus.

Wei S, Yoshida N, Finn G, Kozono S, Nechama M, Kyttaris VC, Zhen Zhou X, Tsokos GC, Ping Lu K. Wei S, et al. Arthritis Rheumatol. 2016 Oct;68(10):2503-13. doi: 10.1002/art.39741. Arthritis Rheumatol. 2016. PMID: 27159270 Free PMC article.

4

Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's disease.

Driver JA, Zhou XZ, Lu KP. Driver JA, et al. Biochim Biophys Acta. 2015 Oct;1850(10):2069-76. doi: 10.1016/j.bbagen.2014.12.025. Epub 2015 Jan 10. Biochim Biophys Acta. 2015. PMID: 25583562 Free PMC article. Review.

5

Targeting Prion-like Cis Phosphorylated Tau Pathology in Neurodegenerative Diseases.

Albayram O, Angeli P, Bernstein E, Baxley S, Gao Z, Lu KP, Zhou XZ. Albayram O, et al. J Alzheimers Dis Parkinsonism. 2018;8(3):443. doi: 10.4172/2161-0460.1000443. Epub 2018 Jun 29. J Alzheimers Dis Parkinsonism. 2018. PMID: 30197831 Free PMC article.

6

Pin1 inhibition exerts potent activity against acute myeloid leukemia through blocking multiple cancer-driving pathways.

Lian X, Lin YM, Kozono S, Herbert MK, Li X, Yuan X, Guo J, Guo Y, Tang M, Lin J, Huang Y, Wang B, Qiu C, Tsai CY, Xie J, Gao ZJ, Wu Y, Liu H, Zhou XZ, Lu KP, Chen Y. Lian X, et al. J Hematol Oncol. 2018 May 30;11(1):73. doi: 10.1186/s13045-018-0611-7. J Hematol Oncol. 2018. PMID: 29848341 Free PMC article.

7

Regulation of protein conformation by Pin1 offers novel disease mechanisms and therapeutic approaches in Alzheimer's disease.

Driver JA, Zhou XZ, Lu KP. Driver JA, et al. Discov Med. 2014 Feb;17(92):93-9. Discov Med. 2014. PMID: 24534472 Free PMC article. Review.

8

Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells.

Kozono S, Lin YM, Seo HS, Pinch B, Lian X, Qiu C, Herbert MK, Chen CH, Tan L, Gao ZJ, Massefski W, Doctor ZM, Jackson BP, Chen Y, Dhe-Paganon S, Lu KP, Zhou XZ. Kozono S, et al. Nat Commun. 2018 Aug 9;9(1):3069. doi: 10.1038/s41467-018-05402-2. Nat Commun. 2018. PMID: 30093655 Free PMC article.

9

Pin1 inhibition potently suppresses gastric cancer growth and blocks PI3K/AKT and Wnt/β-catenin oncogenic pathways.

Zhang Z, Yu W, Zheng M, Liao X, Wang J, Yang D, Lu W, Wang L, Zhang S, Liu H, Zhou XZ, Lu KP. Zhang Z, et al. Mol Carcinog. 2019 Aug;58(8):1450-1464. doi: 10.1002/mc.23027. Epub 2019 Apr 26. Mol Carcinog. 2019. PMID: 31026381 Free PMC article.

10

Pin1 inhibition reverses the acquired resistance of human hepatocellular carcinoma cells to Regorafenib via the Gli1/Snail/E-cadherin pathway.

Wang J, Zhang N, Han Q, Lu W, Wang L, Yang D, Zheng M, Zhang Z, Liu H, Lee TH, Zhou XZ, Lu KP. Wang J, et al. Cancer Lett. 2019 Mar 1;444:82-93. doi: 10.1016/j.canlet.2018.12.010. Epub 2018 Dec 21. Cancer Lett. 2019. PMID: 30583078 Free PMC article.

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