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Year Number of Results
2015 1
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2017 1
2018 3
2019 5
2020 4
2021 3
2022 4
2023 3
2024 4

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Page 1
Moonlighting with WDR5: A Cellular Multitasker.
Guarnaccia AD, Tansey WP. Guarnaccia AD, et al. J Clin Med. 2018 Jan 30;7(2):21. doi: 10.3390/jcm7020021. J Clin Med. 2018. PMID: 29385767 Free PMC article. Review.
Targeting MYC through WDR5.
Thomas LR, Adams CM, Fesik SW, Eischen CM, Tansey WP. Thomas LR, et al. Mol Cell Oncol. 2020 Jan 10;7(2):1709388. doi: 10.1080/23723556.2019.1709388. eCollection 2020. Mol Cell Oncol. 2020. PMID: 32158922 Free PMC article.
Targeting WDR5: A WINning Anti-Cancer Strategy?
Aho ER, Weissmiller AM, Fesik SW, Tansey WP. Aho ER, et al. Epigenet Insights. 2019 Jul 18;12:2516865719865282. doi: 10.1177/2516865719865282. eCollection 2019. Epigenet Insights. 2019. PMID: 31360909 Free PMC article.
Mitotic gene regulation by the N-MYC-WDR5-PDPK1 nexus.
Streeter SA, Williams AG, Evans JR, Wang J, Guarnaccia AD, Florian AC, Al-Tobasei R, Liu Q, Tansey WP, Weissmiller AM. Streeter SA, et al. BMC Genomics. 2024 Apr 11;25(1):360. doi: 10.1186/s12864-024-10282-6. BMC Genomics. 2024. PMID: 38605297 Free PMC article.
Inhibition of MYC by the SMARCB1 tumor suppressor.
Weissmiller AM, Wang J, Lorey SL, Howard GC, Martinez E, Liu Q, Tansey WP. Weissmiller AM, et al. Nat Commun. 2019 May 1;10(1):2014. doi: 10.1038/s41467-019-10022-5. Nat Commun. 2019. PMID: 31043611 Free PMC article.
WIN site inhibition disrupts a subset of WDR5 function.
Siladi AJ, Wang J, Florian AC, Thomas LR, Creighton JH, Matlock BK, Flaherty DK, Lorey SL, Howard GC, Fesik SW, Weissmiller AM, Liu Q, Tansey WP. Siladi AJ, et al. Sci Rep. 2022 Feb 3;12(1):1848. doi: 10.1038/s41598-022-05947-9. Sci Rep. 2022. PMID: 35115608 Free PMC article.
Discovery of WD Repeat-Containing Protein 5 (WDR5)-MYC Inhibitors Using Fragment-Based Methods and Structure-Based Design.
Chacón Simon S, Wang F, Thomas LR, Phan J, Zhao B, Olejniczak ET, Macdonald JD, Shaw JG, Schlund C, Payne W, Creighton J, Stauffer SR, Waterson AG, Tansey WP, Fesik SW. Chacón Simon S, et al. J Med Chem. 2020 Apr 23;63(8):4315-4333. doi: 10.1021/acs.jmedchem.0c00224. Epub 2020 Apr 9. J Med Chem. 2020. PMID: 32223236 Free PMC article.
27 results