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ESR1 mutations in breast cancer.
Dustin D, Gu G, Fuqua SAW. Dustin D, et al. Cancer. 2019 Nov 1;125(21):3714-3728. doi: 10.1002/cncr.32345. Epub 2019 Jul 18. Cancer. 2019. PMID: 31318440 Free PMC article. Review.
Hormonal modulation of ESR1 mutant metastasis.
Gu G, Tian L, Herzog SK, Rechoum Y, Gelsomino L, Gao M, Du L, Kim JA, Dustin D, Lo HC, Beyer AR, Edwards DG, Gonzalez T, Tsimelzon A, Huang HJ, Fernandez NM, Grimm SL, Hilsenbeck SG, Liu D, Xu J, Alaniz A, Li S, Mills GB, Janku F, Kittler R, Zhang XH, Coarfa C, Foulds CE, Symmans WF, Andò S, Fuqua SAW. Gu G, et al. Oncogene. 2021 Feb;40(5):997-1011. doi: 10.1038/s41388-020-01563-x. Epub 2020 Dec 15. Oncogene. 2021. PMID: 33323970 Free PMC article.
RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer.
Dustin D, Gu G, Beyer AR, Herzog SK, Edwards DG, Lin H, Gonzalez TL, Grimm SL, Coarfa C, Chan DW, Kim BJ, De La O JP, Ellis MJ, Liu D, Li S, Welm AL, Fuqua SAW. Dustin D, et al. Br J Cancer. 2021 Jan;124(1):191-206. doi: 10.1038/s41416-020-01174-z. Epub 2020 Dec 1. Br J Cancer. 2021. PMID: 33257837 Free PMC article.
A combinatorial biomarker predicts pathologic complete response to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2+ breast cancer.
Veeraraghavan J, De Angelis C, Mao R, Wang T, Herrera S, Pavlick AC, Contreras A, Nuciforo P, Mayer IA, Forero A, Nanda R, Goetz MP, Chang JC, Wolff AC, Krop IE, Fuqua SAW, Prat A, Hilsenbeck SG, Weigelt B, Reis-Filho JS, Gutierrez C, Osborne CK, Rimawi MF, Schiff R. Veeraraghavan J, et al. Ann Oncol. 2019 Jun 1;30(6):927-933. doi: 10.1093/annonc/mdz076. Ann Oncol. 2019. PMID: 30903140 Free PMC article.
Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets.
Gates LA, Gu G, Chen Y, Rohira AD, Lei JT, Hamilton RA, Yu Y, Lonard DM, Wang J, Wang SP, Edwards DG, Lavere PF, Shao J, Yi P, Jain A, Jung SY, Malovannaya A, Li S, Shao J, Roeder RG, Ellis MJ, Qin J, Fuqua SAW, O'Malley BW, Foulds CE. Gates LA, et al. Oncogene. 2018 Aug;37(33):4581-4598. doi: 10.1038/s41388-018-0284-2. Epub 2018 May 11. Oncogene. 2018. PMID: 29748621 Free PMC article.