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Mitochondrial superoxide targets energy metabolism to modulate epigenetic regulation of NRF2-mediated transcription.
Free Radic Biol Med. 2022 Feb 1;179:181-189. doi: 10.1016/j.freeradbiomed.2021.12.309. Epub 2021 Dec 28.
Free Radic Biol Med. 2022.
PMID: 34968705
Free PMC article.
UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation.
Dhar SK, Batinic-Haberle I, St Clair DK.
Dhar SK, et al.
J Biol Chem. 2019 Apr 26;294(17):6831-6842. doi: 10.1074/jbc.RA118.006595. Epub 2019 Mar 11.
J Biol Chem. 2019.
PMID: 30858178
Free PMC article.
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DNA polymerase gamma (Polγ) deficiency triggers a selective mTORC2 prosurvival autophagy response via mitochondria-mediated ROS signaling.
Dhar SK, Bakthavatchalu V, Dhar B, Chen J, Tadahide I, Zhu H, Gao T, St Clair DK.
Dhar SK, et al.
Oncogene. 2018 Nov;37(48):6225-6242. doi: 10.1038/s41388-018-0404-z. Epub 2018 Jul 23.
Oncogene. 2018.
PMID: 30038268
Free PMC article.
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