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Year Number of Results
2020 8
2021 5
2022 9
2023 7
2024 0

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26 results

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Page 1
Targeting RNA structures with small molecules.
Childs-Disney JL, Yang X, Gibaut QMR, Tong Y, Batey RT, Disney MD. Childs-Disney JL, et al. Nat Rev Drug Discov. 2022 Oct;21(10):736-762. doi: 10.1038/s41573-022-00521-4. Epub 2022 Aug 8. Nat Rev Drug Discov. 2022. PMID: 35941229 Free PMC article. Review.
Programming inactive RNA-binding small molecules into bioactive degraders.
Tong Y, Lee Y, Liu X, Childs-Disney JL, Suresh BM, Benhamou RI, Yang C, Li W, Costales MG, Haniff HS, Sievers S, Abegg D, Wegner T, Paulisch TO, Lekah E, Grefe M, Crynen G, Van Meter M, Wang T, Gibaut QMR, Cleveland JL, Adibekian A, Glorius F, Waldmann H, Disney MD. Tong Y, et al. Nature. 2023 Jun;618(7963):169-179. doi: 10.1038/s41586-023-06091-8. Epub 2023 May 24. Nature. 2023. PMID: 37225982 Free PMC article.
Fragment-Based Approaches to Identify RNA Binders.
Suresh BM, Taghavi A, Childs-Disney JL, Disney MD. Suresh BM, et al. J Med Chem. 2023 May 25;66(10):6523-6541. doi: 10.1021/acs.jmedchem.3c00034. Epub 2023 May 15. J Med Chem. 2023. PMID: 37186875 Free PMC article. Review.
Small molecule recognition of disease-relevant RNA structures.
Meyer SM, Williams CC, Akahori Y, Tanaka T, Aikawa H, Tong Y, Childs-Disney JL, Disney MD. Meyer SM, et al. Chem Soc Rev. 2020 Oct 5;49(19):7167-7199. doi: 10.1039/d0cs00560f. Chem Soc Rev. 2020. PMID: 32975549 Free PMC article. Review.
Design of small molecules targeting RNA structure from sequence.
Ursu A, Childs-Disney JL, Andrews RJ, O'Leary CA, Meyer SM, Angelbello AJ, Moss WN, Disney MD. Ursu A, et al. Chem Soc Rev. 2020 Oct 19;49(20):7252-7270. doi: 10.1039/d0cs00455c. Chem Soc Rev. 2020. PMID: 32935689 Free PMC article. Review.
26 results