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2022 2
2023 12
2024 3

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Page 1
Topography of mutational signatures in human cancer.
Otlu B, Díaz-Gay M, Vermes I, Bergstrom EN, Zhivagui M, Barnes M, Alexandrov LB. Otlu B, et al. Cell Rep. 2023 Aug 29;42(8):112930. doi: 10.1016/j.celrep.2023.112930. Epub 2023 Aug 4. Cell Rep. 2023. PMID: 37540596 Free PMC article.
Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers.
Thatikonda V, Islam SMA, Autry RJ, Jones BC, Gröbner SN, Warsow G, Hutter B, Huebschmann D, Fröhling S, Kool M, Blattner-Johnson M, Jones DTW, Alexandrov LB, Pfister SM, Jäger N. Thatikonda V, et al. Nat Cancer. 2023 Feb;4(2):276-289. doi: 10.1038/s43018-022-00509-4. Epub 2023 Jan 26. Nat Cancer. 2023. PMID: 36702933 Free PMC article.
Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response.
Pagadala M, Sears TJ, Wu VH, Pérez-Guijarro E, Kim H, Castro A, Talwar JV, Gonzalez-Colin C, Cao S, Schmiedel BJ, Goudarzi S, Kirani D, Au J, Zhang T, Landi T, Salem RM, Morris GP, Harismendy O, Patel SP, Alexandrov LB, Mesirov JP, Zanetti M, Day CP, Fan CC, Thompson WK, Merlino G, Gutkind JS, Vijayanand P, Carter H. Pagadala M, et al. Nat Commun. 2023 May 12;14(1):2744. doi: 10.1038/s41467-023-38271-5. Nat Commun. 2023. PMID: 37173324 Free PMC article.
Arsenic is a potent co-mutagen of ultraviolet light.
Speer RM, Nandi SP, Cooper KL, Zhou X, Yu H, Guo Y, Hudson LG, Alexandrov LB, Liu KJ. Speer RM, et al. bioRxiv [Preprint]. 2023 Feb 23:2023.02.22.529578. doi: 10.1101/2023.02.22.529578. bioRxiv. 2023. PMID: 36865271 Free PMC article. Updated. Preprint.
Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor.
Islam SMA, Díaz-Gay M, Wu Y, Barnes M, Vangara R, Bergstrom EN, He Y, Vella M, Wang J, Teague JW, Clapham P, Moody S, Senkin S, Li YR, Riva L, Zhang T, Gruber AJ, Steele CD, Otlu B, Khandekar A, Abbasi A, Humphreys L, Syulyukina N, Brady SW, Alexandrov BS, Pillay N, Zhang J, Adams DJ, Martincorena I, Wedge DC, Landi MT, Brennan P, Stratton MR, Rozen SG, Alexandrov LB. Islam SMA, et al. Cell Genom. 2022 Nov 9;2(11):None. doi: 10.1016/j.xgen.2022.100179. Cell Genom. 2022. PMID: 36388765 Free PMC article.
Arsenic is a potent co-mutagen of ultraviolet light.
Speer RM, Nandi SP, Cooper KL, Zhou X, Yu H, Guo Y, Hudson LG, Alexandrov LB, Liu KJ. Speer RM, et al. Commun Biol. 2023 Dec 16;6(1):1273. doi: 10.1038/s42003-023-05659-4. Commun Biol. 2023. PMID: 38104187 Free PMC article.
17 results