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SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions.
J Clin Invest. 2023 Jul 3;133(13):e165988. doi: 10.1172/JCI165988.
J Clin Invest. 2023.
PMID: 37166989
Free PMC article.
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling.
Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E.
Ng VH, et al.
Nat Commun. 2023 Oct 5;14(1):6173. doi: 10.1038/s41467-023-41836-z.
Nat Commun. 2023.
PMID: 37798301
Free PMC article.
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The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6.
Spencer ZT, Ng VH, Benchabane H, Siddiqui GS, Duwadi D, Maines B, Bryant JM, Schwarzkopf A, Yuan K, Kassel SN, Mishra A, Pimentel A, Lebensohn AM, Rohatgi R, Gerber SA, Robbins DJ, Lee E, Ahmed Y.
Spencer ZT, et al.
Nat Commun. 2023 Oct 5;14(1):6174. doi: 10.1038/s41467-023-41843-0.
Nat Commun. 2023.
PMID: 37798281
Free PMC article.
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Molecular signature incorporating the immune microenvironment enhances thyroid cancer outcome prediction.
Xu GJ, Loberg MA, Gallant JN, Sheng Q, Chen SC, Lehmann BD, Shaddy SM, Tigue ML, Phifer CJ, Wang L, Saab-Chalhoub MW, Dehan LM, Wei Q, Chen R, Li B, Kim CY, Ferguson DC, Netterville JL, Rohde SL, Solórzano CC, Bischoff LA, Baregamian N, Shaver AC, Mehrad M, Ely KA, Byrne DW, Stricker TP, Murphy BA, Choe JH, Kagohara LT, Jaffee EM, Huang EC, Ye F, Lee E, Weiss VL.
Xu GJ, et al.
Cell Genom. 2023 Sep 14;3(10):100409. doi: 10.1016/j.xgen.2023.100409. eCollection 2023 Oct 11.
Cell Genom. 2023.
PMID: 37868034
Free PMC article.
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